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The ICP-MS Journal

February 2026

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Message from the Editor

This edition of The ICP-MS Journal marks over one year of the online version. If you’ve been with us since the first edition, thank you. If you’re a new reader, welcome, and please subscribe to stay updated when we release the next editions.

In each edition, we feature four new articles that you hopefully find interesting, helpful, and even entertaining. The articles remain “evergreen,” meaning they will always be available to read. Just scroll to the Recent Articles section, where you’ll be able to read (and watch) all of the previous Featured Articles.

As it’s a belated birthday, I would love any feedback you may have, so drop me an email or use the feedback tab in the browser. This will help us understand what we’re doing well and what you’d like to see more of in future editions.

Also, if you have any interesting applications, research, or anything that would benefit the ICP-MS community, drop me a line, and we can work on an article together.

Thanks
Glenn Woods
editor.the_icp-ms_journal@agilent.com

Lithium-Ion Battery Manufacturing: Trace Contaminant Analysis by ICP-MS

Lithium-Ion Batteries (LIBs) power our devices and electric vehicles, and are key to renewable energy storage. Advanced ICP-MS tools enable sensitive analysis of trace elements, boosting research and quality control.

Protect Your ICP-MS Investment: Cone Selection and Maintenance for Peak Performance

Discover the Agilent ICP-MS Interface Cones FAQs—your guide to optimizing performance. Learn about cone types, features, selection tips, and maintenance for peak results.

ICP-MS Quick Tips: Using ICP-MS MassHunter Sublists

Modern labs process numerous samples monthly, needing flexible, user-friendly instruments. ICP-MS MassHunter's 'sublist' feature lets users create customizable analyte lists, enabling targeted measurements with a single method. Here's how to set up and use sublists.

Semiconductor Focus Part 3: Complex materials and matrices

This article uncovers cutting-edge automated techniques for analyzing semiconductor silicon, wide-bandgap substrates, and contamination control in IC-grade photoresist—crucial for maintaining top-tier quality and consistency in semiconductor manufacturing. Stay ahead with ICP-QQQ technology.

Chromium Speciation in Water Using Integrated IC−ICP−MS

Explore how a Metrohm Ion Chromatograph (IC) seamlessly works with an Agilent ICP-MS, using the Agilent ICP-MS MassHunter software. This ISO 24384-compliant method not only provides top sensitivity and accuracy but also delivers impressive efficiency and analytical performance.

Reflections on 2025 European Winter Conference on Plasma Spectrochemistry

Based on over 150 conference posters, ICP-MS dominates in current plasma spectrochemistry research, with increasing use of hyphenated methods for single-particle and single-cell studies. We look at the recent EWCPS.

Agilent ICP-MS MassHunter Software Version 5.4

Software version 5.4 introduces exciting advancements in trace element analysis, transforming how high-purity reagents are tested. By streamlining workflows for both routine and advanced applications and improving single-nanoparticle (sNP) analysis, these updates empower industry professionals. Designed to enhance ICP-MS applications, especially in the semiconductor industry.

Semiconductor Focus Part 2: High-purity organics by ICP-QQQ

Building on our semiconductor focus, this review explores the innovative applications of ICP-QQQ technology. Dive into how this cutting-edge technique enables the precise detection of both dissolved and particulate contaminants in high-purity organic chemicals and solvents, highlighting its crucial role in advancing material purity and industry standards.

New ADS 2 Autodilution System

The ADS 2 is an innovative new sample automation system for ICP-MS and ICP-OES. This article looks at both the ADS 2 as well as the UHMI gas dilution system and how they can work together.

ADS 2 Applications for High Matrix Samples

Practical applications of the ADS 2 with Agilent ICP-MS instruments highlight enhanced laboratory efficiency achieved through a reduction in the analyst’s workload.

ICP-MS MassHunter Version 5.3 with Star Rating

The latest version of ICP-MS MassHunter features advanced controls for the ADS 2 autodilutor. IntelliQuant has been updated to make it even better and has been given an exciting new data analysis feature known as Star Rating.

Ultratrace Boron Analysis using the 8900 ICP-QQQ

Boron and 35 other elements were determined in ultrapure water by the Agilent ICP-QQQ. The boron background was controlled using a UPW system with a B-filter, enabling a ppq-level detection limit to be achieved.

Imaging Metals in Biological Samples by Laser Ablation (LA)-ICP-MS

ICP-MS and ICP-QQQ coupled with laser ablation are used to map elemental distributions in tissue samples. These elemental maps help research the role that different elements have in certain short-term or chronic conditions. The article looks at a heart section after suffering a myocardial infarction (MI) as well as a liver section.

Overcoming ICP-MS Signal Enhancement in Food Analysis by Adding CO2 to the Plasma

A food analysis company adds carbon dioxide to the ICP-QQQ plasma using a novel in-house designed maniford to increase sensitivity and reduce sample-to-sample ionization variability in carbon-containing samples.

ICP-MS Quick Tips: Configuring ICP-MS MassHunter Custom Views

The first in a series of ICP-MS Quick Tips, where we look at a useful tip in five minutes or less. This article focuses of configuring ICP-MS MassHunter data analysis custom layout and data view options, providing you with tools to streamline your data analysis process.

Semiconductor Focus Part I: Aqueous-based applications of ICP-QQQ

Continuing our focus on semiconductors, we look at a review of ICP-QQQ applications. This part I review examines semiconductor aqueous-based chemical analysis applications and the unique challenges faced by the semiconductor industry.

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