5977C Inert Plus GC/MSD
5977C GC/MSD
At Agilent we continuously strive for innovation. The new HydroInert source for hydrogen carrier applications not only minimizes disruptions from helium shortages but also improves spectral fidelity, peak shape, and sensitivity when running with hydrogen. System intelligence, like remote monitoring and email-based instrument health alerts, make system monitoring easier and more actionable. Together, these new capabilities on the 5977C GC/MSD improve sample throughput and analytical performance, enabling better business outcomes for your lab.
- GC/MS Instruments
Product Details
- Detection limits as low as 1 fg IDL assert reliability and sensitivity for your analyses
- The new HydroInert source improves chromatographic efficiency for hydrogen carrier gas applications and minimizes loss in sensitivity and spectral anomalies associated with H2 gas
- JetClean self-cleaning ion source greatly reduces or even eliminates the need for manual source cleaning
- Built-in intelligence of the 8890, 8850, 8860, and Intuvo 9000 GCs enhances productivity with smart diagnostics, monitoring, and simplified access to powerful operations through the integrated touch screen and browser interface
- Inert Flow Path products like columns, liners, inlets, gold seals, and ferrules improve mass spectrometry workflows and ensure inertness with every surface that touches your sample
- Agilent CrossLab Smart Alerts software uses email-based alerts to notify you when to consider replacing key consumables and when an instrument stops running anywhere in your lab; plan your preventive maintenance and monitor instrument health remotely
- MassHunter Unknowns Analysis allows you to develop new methods with fast and reliable compound identification using its ability to create custom retention time locked spectral libraries
- MassHunter Review by Exception and Compounds at a Glance simplify and speed up data analysis and review
- Cerno Bioscience MassWorks MS calibration technology enables high mass accuracy on the 5977C GC/MSD
- To enable a better-informed, sustainable choice, Agilent has partnered with My Green Lab to have the 5977C GC/MSD independently audited for their Accountability, Consistency, and Transparency (ACT) label
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Gas Chromatography Mass Spectrometry (GC-MS) Information
What is GC-MS? GC/MS combines two analytical tools to identify and measure the concentration of chemicals found in foods, consumer products, pharmaceuticals, fuels, the environment, and more. Read on to learn more about the typical components of a GC/MS instrument and its basic principle of operation.
Learn More- Application Notes
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Analysis of Epichlorohydrin in Drinking Water
This study demonstrates the capability of the Teledyne LABS Tekmar Atomx XYZ P&T concentrator to process low‑level ECH in drinking water samples.
- Application Notes
- English
- 20 Nov 2025
- 690.26 KB
Improved Thermal Stability of DB-5Q GC Column for Trace Level Controlled Substances
Increased thermal stability of the DB-5Q GC column with increased signal-to-noise for trace level concentrations of controlled substances results in improved quantitation of analytes.
- Application Notes
- English
- 21 Sep 2025
- 322.40 KB
Improved Determination of Polychlorinated Biphenyl Compounds by US EPA Method 1628
Evaluating 209 PCBs congeners by GC/MS using the Agilent 8890/5977C GC/MSD equipped with the Agilent HydroInert ion source and Agilent J&W DB-XLB column.
- Application Notes
- English
- 21 Sep 2025
- 630.60 KB
A More Sustainable Analysis of Ethylene Oxide and 1,4-Dioxane in Surfactants with Hydrogen Carrier Gas
Ethylene oxide (EO) and 1,4-dioxane are critical industrial chemicals often found as residuals in surfactant production.
- Application Notes
- English
- 29 Jul 2025
- 533.77 KB
Analysis of Trace Permanent Gases and Greenhouse Gases Using Agilent 5977C GC/MSD and HES
This application note presents a solution for the determination of 10 trace permanent gases and greenhouse gases using the Agilent 5977C GC/MSD with high-efficiency source (HES). The solution demonstrates exceptional sensitivity with detection limits down to the ppb level, as well as excellent repeatability and linearity. It is suitable for carbon dioxide reduction (CO2) gas detection, greenhouse gas analysis, and permanent gas impurity analysis in hydrogen (H2) for vehicular fuel applications.
- Application Notes
- English
- 16 Jul 2025
- 1.08 MB
Analysis of Total Aromatic Content in Motor Gasoline by ASTM D5769 Using an Agilent 8850/5977C GC/MSD System
This application note demonstrates the rapid quantification of total aromatics in gasoline by ASTM D5769 using an 8850 GC with a 5977C GC/MSD and hydrogen carrier gas.
- Application Notes
- English
- 07 Jul 2025
- 810.24 KB
Retention Time Stability and Improved Data Accuracy in Pesticide Analysis with GC/MS
Increased thermal stability leads to retention time stability and data accuracy for GC/MS analysis of pesticides with J&W DB-5Q and HP-5Q columns
- Application Notes
- English
- 27 Jun 2025
- 694.45 KB
A Chemometric Approach for Ambient Air Monitoring Using Thermal Desorption GC/MS
Standard method for monitoring VOCs in air
- Application Notes
- English
- 27 Jun 2025
- 1.46 MB
Analysis of Phthalates Using the Agilent 5977C GC/MSD with Hydrogen Carrier Gas
A method for the successful analysis of phthalates with excellent peak shape, resolution, and sensitivity, using hydrogen carrier gas with the Agilent 8890 GC.
- Application Notes
- English
- 13 May 2025
- 1.76 MB
Determination of Polychlorinated Biphenyl (PCB) by GC/MS According to EPA Method 1628
Evaluating 209 PCBs congeners by GC/MS
- Application Notes
- English
- 26 Feb 2025
- 483.20 KB
- Brochures
- Case Studies
- Flyers
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- Technical Overviews
- FAQs
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Instrument Detection Limit Frequently Asked Questions (FAQ)
An Introduction to Using Instrument Detection Limit as a Performance Metric
How do I Troubleshoot 597x NCI Tune Problems in MassHunter?
How do I Troubleshoot 597x NCI Tune Problems in MassHunter?
Can I Run My Instrument with a High Vacuum Reading of 9.99x10-9?
Can I Run My Instrument with a High Vacuum Reading of 9.99x10-9?
FAQ: Can Hydrogen be Use Instead of Helium for My GCMSD?
FAQ: I want to change our GCMSD lab carrier gas over to hydrogen. Is it as easy as just changing the tank or is there more to consider?
KB000390: What does error ''Difficulty with mass filter electronics, cannot achieve constant peak widths'' indicate?
Information relating to error message Difficulty with mass filter electronics, cannot achieve constant peak widths''
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Agustin Pierri, Ph.D.
Laboratory Technical Director, Weck Laboratories, Inc.
"Agilent gave us the best performance meaning the most sensitivity, the best reliability, but also the best value."
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Senior Scientific Advisor, Nelson Labs
“We chose Agilent as our main instrument vendor, because simply they are good instruments.”
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Agilent 8850 GC with Expanded Capabilities Lets You Do More Than Before
The fast, compact, energy-efficient 8850 GC has new features that enable more labs to perform more methods and process more samples. It is now compatible with Agilent single quadrupole and triple quadrupole mass spectrometers. The Multimode Inlet provides greater sample introduction flexibility. A PAL3 Series 2 autosampler system significantly increases sample capacity and allows comprehensive automated sample preparation. A higher maximum oven temperature expands the number of applications that are possible. Backflush improves lab productivity and lowers operating costs.
- 18 May 2025
Agilent Launches New J&W Ultra Inert Columns with Ultra Low-Bleed Technology
The new J&W 5Q columns combine Agilent's industry-leading Ultra Inert performance with Ultra Low-Bleed technology, delivering the new standard for MS column performance and productivity. 5Q columns provide exceptional peak symmetry and minimal column bleed enabling high sensitivity, mass spectral integrity, and accurate quantitation for the most challenging, trace-level analytes. 5Q columns are also designed to optimize sample throughput with fast conditioning and outstanding durability even at high operating temperatures.
- 01 Aug 2024