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Advance Throughput and Resolution, Even for Highly Polar Analytes

New Agilent InfinityLab Poroshell 120 Aq-C18 columns

Retain challenging polar compounds with 100% aqueous mobile phases

Master your polar molecules with new InfinityLab Poroshell 120 Aq-C18 columns.

They deliver enhanced polar compound retention, and are compatible with 100% aqueous mobile phases without phase collapse or dewetting. So, you can confidently develop separations that retain polar and nonpolar compounds together.

These columns are the latest addition to the Agilent InfinityLab Poroshell 120 portfolio of superficially porous particle columns for HPLC and UHPLC applications. With 20 chemistries and three particle sizes, InfinityLab Poroshell 120 columns let you achieve fast, adaptable method development across instruments and labs.

Agilent InfinityLab Poroshell 120 Aq-C18 columns flyer

Are you developing separations consisting of polar and nonpolar analytes?

With the new InfinityLab Poroshell 120 Aq-C18 columns, you can now maximize reversed-phase retention for highly polar analytes with 100% aqueous mobile phases.

Confidently perform fast, rugged LC

InfinityLab Poroshell 120 columns are based on superficially porous particle technology, which features a solid silica core and a porous outer layer. Compared to traditional totally porous particles of the same (or similar) size, Poroshell particles deliver higher chromatographic efficiencies and enable fast, high-resolution separations.

  • Exceptional separation efficiency and reliability
  • Broad choice of selectivity for scalable and fast LC method development
  • Twenty chemistries—from various C18 columns to other unique phases—available in up to three particle sizes: 1.9 µm, 2.7 µm, and 4 µm
Agilent InfinityLab Poroshell 120 columns

Get more from your methods with scalable particle sizes in superficially porous particles

InfinityLab Poroshell 120 columns are available in three particle sizes to fit all your separation needs and to make method transfer easier than ever.

1.9 µm

Highest UHPLC performance

  • Get up to 20% more efficiency for your UHPLC separations.
  • Reach new levels of throughput by ultrafast separations.

2.7 µm

UHPLC-like performance at HPLC pressures

  • Double your number of samples analyzed per day.
  • Reach UHPLC performance and HPLC robustness.

4 µm

Improved HPLC performance within your comfort zone

  • Achieve 200% separation efficiency with 0% disruption.
  • Adjust isocratic USP compendial methods without revalidation.

Experience exceptional separation efficiency under a wide range of conditions

Perform fast, high-efficiency chiral separations

InfinityLab Poroshell 120 chiral columns combine superficially porous particles with innovative chiral stationary phases. They deliver better performance and speed compared to totally porous chiral stationary phases for increased throughput with more efficient chiral separations.

Agilent InfinityLab Poroshell 120 chiral columns

Analyze challenging polar compounds

InfinityLab Poroshell 120 HILIC chemistries allow you to retain and separate small polar analytes by using a standard LC system and common reversed-phase solvents. Advantages include superior retention of highly charged polar analytes providing fast, high-efficiency separations.

Agilent InfinityLab Poroshell 120 HILIC columns

Purify with confidence

Achieve reliable small molecule separations, seamless scale-up, and long column lifetimes with InfinityLab preparative HPLC columns. Together with InfinityLab LC purification systems and software, these can help you achieve your purification goals.

Agilent InfinityLab preparative HPLC columns

Make every step of your LC workflow run more smoothly

Save time and minimize troubleshooting

The “small” parts of your workflow can make a big difference in the quality of your results. Agilent InfinityLab supplies are innovatively designed to make your daily tasks more efficient. Shop now

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Get column facts at-a-glance

Choosing the right column depends on many variables, such as chemistry type, temperature limits, and USP designation. To make it easier, we created a quick-reference LC column selection poster. Download poster

Poroshell 120 poster

Column selection made easy

Our LC column selection tool helps you choose the best column for your application based on factors, such as USP designation, phase chemistry, and agency methods. Try it now

HPLC & LC Column Selector Tool

Don’t miss our popular column lifetime webinar

Want to maximize HPLC column lifetime and reliability? Join our on-demand webinar and learn how to protect your HPLC columns from pitfalls like early failure, clogging, and performance loss. View webinar

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Ready to advance your HPLC and UHPLC capabilities?

Explore now