InfinityLab Poroshell HPLC Columns with sustainable packaging
InfinityLab Poroshell 120 HILIC Columns
InfinityLab Poroshell 120 HILIC columns for hydrophilic interaction liquid chromatography (HILIC) are designed for the retention and high-resolution separation of small polar analytes. The superficially porous character of the particles decreases equilibration times to improve throughput for both isocratic and gradient separations. Agilent offers three unique, orthogonal HILIC phases: bare silica (HILIC), polyhydroxy fructan (HILIC-OH5), and zwitterionic (HILIC-Z).
The robustness and reproducibility of HILIC separations on Poroshell columns help to switch from challenging, often MS-incompatible ion pair chromatography and normal phase applications.
The new Altura Poroshell HILIC-Z columns enhance Poroshell HILIC-Z with Ultra Inert column hardware. This configuration is particularly beneficial for the analysis of metal-sensitive polar compounds, helping to reduce secondary interactions that can affect peak shape and recovery. Application resources below highlight the advantages of Altura HILIC-Z for GLP-1 impurity profiling and hydrophilic metabolites.
*Please see document 5994-4414EN below for important information concerning PEEK-lined hardware.
The robustness and reproducibility of HILIC separations on Poroshell columns help to switch from challenging, often MS-incompatible ion pair chromatography and normal phase applications.
The new Altura Poroshell HILIC-Z columns enhance Poroshell HILIC-Z with Ultra Inert column hardware. This configuration is particularly beneficial for the analysis of metal-sensitive polar compounds, helping to reduce secondary interactions that can affect peak shape and recovery. Application resources below highlight the advantages of Altura HILIC-Z for GLP-1 impurity profiling and hydrophilic metabolites.
*Please see document 5994-4414EN below for important information concerning PEEK-lined hardware.
Product Details
Features
- Superficially porous, 'core-shell' particles that provide improved throughput, shorter equilibration times, and higher resolution
- A scalable family of particles—1.9 μm, 2.7 μm, and 4 μm—enable you to get the best from your methods and instruments
- Separate many polar compound classes by choosing from orthogonal bare silica (HILIC), poly-hydroxy fructan (HILIC-OH5), or zwitterionic (HILIC-Z) phases
- Fully compatible with Agilent InfinityLab deactivator additive, which mproves sensitivity in challenging analyses of phosphorylated and carboxylated compounds with stainless steel LC/MS systems
- Part of the InfinityLab family - designed for ease-of-use and maximum compatibility with Agilent instruments and supplies
- Long column life with uniquely robust 1.9 μm low-dispersion UHPLC columns
- Reduced need for sample preparation due to 2 μm frits on 2.7 μm and 4 μm columns
- UHPLC guard columns to further extend the life of your analytical column
- Enhanced usability, traceability, and security with a preprogrammed ID tag
Applications
How It Works
Featured References
- Publications
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- Pičmanová, M.; Moses, T.; Cortada-Garcia, J.; Barrett, G.; Florance, H.; Pandor, S.; Burgess, K. Rapid HILIC-Z ion mobility mass spectrometry (RHIMMS) method for untargeted metabolomics of complex biological samples. Metabolomics 2022, 18 (3), 16. DOI: 10.1007/s11306-022-01871-1.