DNA Testing
Measure With Confidence Both Size And Concentration Of DNA Fragments
When samples have insufficient nuclear DNA present for effective analysis (due to damage, degradation or limited sample availability) mitochondrial DNA (mt-DNA) testing can be used to determine the maternal lineage of a DNA sample. The solution is often used to identify remains of service personnel or disaster victims, as well as to analyze historical samples.
Accurately measuring both the size and concentration of DNA fragments prior to analysis is a key challenge in this area. The Agilent 2100 Bioanalyzer and DNA 500 LabChip carry such analyses quickly and effectively to the required precision for further mt-DNA classification. The systems also enable the optimization of PCR analyses through rapid quantitative analysis of both mt-DNA amplification products and PCR artifacts.
DNA Testing Compendium
- PDF/ Found In: Application Notes
- Date : 25 Nov 2012
- File Size : 1.07 MB
- Application Notes
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Fast Determination of Thermal Melt Temperature of Double-Stranded Nucleic Acids by UV-Vis Spectroscopy
Reproducible melting temperature (Tm) data at fast ramp rates using the Agilent Cary 3500 UV-Vis spectrophotometer
- Application Notes
- English
- 17 Aug 2022
- 1.18 MB
Agilent JetClean: In-situ GC/MS Ion Source Cleaning and Conditioning
Application note detailing general operation of JetClean
- Application Notes
- English
- 26 Aug 2016
- 1.78 MB
Strawberry and Raspberry Fruit Differentiation Using the Agilent CE 2100 Bioanalyzer system
Application note for strawberry and raspberry fruit differentiation using the Agilent CE 2100 Bioanalyzer system.
- Application Notes
- English
- 06 Apr 2016
- 302.60 KB
Absolute Real-Time PCR: A Comparison of Spectrophotometric and On-Chip Methods for External Standard Curve Construction from Different Nucleic Acid Dosages
The Bioanalyzer system provides accurate and precise quantitation of DNA, enabling preparation of reliable standard curves for absolute quantitation with qPCR assays.
- Application Notes
- English
- 29 Mar 2016
- 1.46 MB
Agilent Solutions for Removal and Monitoring of Genomic DNA from Monoclonal Antibody Preparations
This Application Note describes an application solution for the removal and monitoring of genomic DNA contamination from monoclonal antibody preparation.
- Application Notes
- English
- 27 Nov 2013
- 987.20 KB
Spanish Version_Achieving Faster Ramp Rates for Thermal Melt Experiments
Same result achieved independent of ramp rate, using the Cary 3500 UV-Vis spectrophotometer
- Application Notes
- Spanish
- 03 Jan 2023
- 264.24 KB
High performance DNA oligonucleotide purification using Agilent TOP-DNA
Because of the significant progress achieved in the solid phase chemical synthesis of oligonucleotides during the past four decades, synthetic oligonucleotides...
- Application Notes
- English
- 26 Sep 2012
- 707.71 KB
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