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Raman Spectroscopy

Innovative Raman Spectrometers Using SORS & TRS for Noninvasive Chemical Analysis

Agilent Raman spectrometers use proprietary spatially offset Raman spectroscopy (SORS) and transmission Raman spectroscopy (TRS) in fields ranging from airport security screening and pharmaceutical quality control, to hazardous chemical identification in the field.

SORS enables our Raman spectrometers to analyze through containers and opaque barriers, from helping first responders identify the contents of suspect packages, to high-throughput raw material identification inside unopened packaging at pharmaceutical quality control. TRS nondestructively screens whole tablets and capsules in seconds, for rapid content uniformity and polymorph analysis in pharma QC and formulation development.

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Raman Spectroscopy FAQ Guide

Learn about how Raman spectroscopy works, the Raman effect, the advantages and disadvantages of Raman, and more.

Raman Spectroscopy Applications Guide

A guide to Raman spectroscopy applications using Agilent handheld and benchtop Raman analyzers.

Molecular Spectroscopy Pharma & Biopharma Solutions Guide

Learn about products & applications in pharma & biopharma using UV-Vis, FTIR, fluorescence, SORS & TRS technology.

TRS Return-on-Investment Value Calculator

See how much and how soon you could save compared to your current content uniformity workflow.

Featured Literature

How Much Are False Alarms Costing You?

Find out how our false alarms might affect your airport’s bottom line with our easy to use calculator tool.

Identification of Oligonucleotide Starting Materials Directly Through Containers

Use of the Agilent Vaya Raman handheld spectrometer for the identification of oligonucleotide starting materials, phosphoramidites, directly through amber bottles.

Solutions for Accelerated Raw Materials Identification

This e-book describes how a through-container handheld Raman instrument can be used to reduce the turn around time and cost of pharmaceutical raw material quality control

Detection of Hazardous Narcotics and New Psychoactive Substances (NPS) with Agilent Resolve—a Handheld SORS System

Use of Resolve allows the examination a maximum range of packages or containers for indications of hazardous materials before disturbing, opening, or taking a sample.

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Featured News

Agilent Resolve Named Coolest Thing Made in Delaware for Life-Saving Innovation

The Agilent Resolve handheld Raman spectrometer was named Delaware’s “Coolest Thing Made” for its role in saving lives globally. Built in Wilmington, Resolve helps emergency teams identify dangerous substances—like explosives or narcotics—through sealed containers. This award celebrates Agilent’s innovation, impact, and commitment to safety and science.

Agilent Launches Insight Series Alarm Resolution Systems for Airport Security Screening

Agilent has announced the launch of its new Insight Series alarm resolution systems, designed to enhance safety and streamline operations at airport security checkpoints worldwide. The Insight Series includes the Insight300M and InsightBLS, advanced liquid explosive detection systems (LEDs) that are designed to meet global regulations for screening liquids, aerosols, and gels (LAGs).

Agilent Transmission Raman Supporting Continuous Manufacturing of Oral Solid Drug Products

This application note explores the use of transmission Raman spectroscopy (TRS) as an at-line quantitative technique for continuous manufacturing of oral solid dose forms. TRS offers rapid, high throughput, near real-time bulk analysis of tablets and capsules.

Featured Training & Events

Boost Productivity and Eliminate Waste in Raw Material ID

Raw material identification (RMID) is a regulatory-enforced step in drug manufacturing for pharmaceutical and biopharmaceutical organizations.
Webinar/Training

Implementing Transmission Raman for Fast Content Uniformity Testing – from Feasibility Evaluation to a Validated Release Method

The webinar highlights the approach that led to the implementation of transmission Raman spectroscopy for content uniformity testing at a pharmaceutical company. The webinar also discusses the reasons for using transmission Raman spectroscopy for content uniformity and how it works in conjunction with established liquid chromatography (LC) methods.
Webinar/Training

Molecular Spectroscopy Webinar Curriculum

Molecular Spectroscopy Webinar Curriculum includes UV-Vis, UV-Vis-NIR, fluorescence, handheld and benchtop FTIR, and Raman systems for high performance and flexibility
Webinar/Training

Spectroscopy Digital Workshops & Bootcamps

Hone your lab skills, outside the lab, with our live, interactive series of virtual workshops and software bootcamps! Learn about the latest in software solutions for Spectroscopy, discuss the entire analytical process from method development to data analysis, and participate in live analytical runs with our experts. We hope these will prepare you for future hands-on events in the future.
Webinar/Training
Featured References
  1. View all spatially offset Raman spectroscopy (SORS) and transmission Raman spectroscopy (TRS) peer-reviewed publications Learn More

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