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Raman Spectroscopy

Innovative Raman Spectrometers for Noninvasive Chemical Analysis

Agilent Raman spectrometers use proprietary spatially offset Raman spectroscopy (SORS) and transmission Raman spectroscopy (TRS) in fields ranging from airport security screening and pharmaceutical quality control, to hazardous chemical identification in the field.

SORS enables our Raman spectrometers to analyze through containers and opaque barriers, from helping first responders identify the contents of suspect packages, to high-throughput raw material identification inside unopened packaging at pharmaceutical quality control. TRS nondestructively screens whole tablets and capsules in seconds, for rapid content uniformity and polymorph analysis in pharma QC and formulation development.
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Featured Tools

Raman Spectroscopy FAQ Guide

Learn about how Raman spectroscopy works, the Raman effect, the advantages and disadvantages of Raman, and more.

Raman Spectroscopy Applications Guide

A guide to Raman spectroscopy applications using Agilent handheld and benchtop Raman analyzers.

Molecular Spectroscopy Pharma & Biopharma Solutions Guide

Learn about products & applications in pharma & biopharma using UV-Vis, FTIR, fluorescence, SORS & TRS technology.

TRS Return-on-Investment Value Calculator

See how much and how soon you could save compared to your current content uniformity workflow.

Featured Literature

Identification of Oligonucleotide Starting Materials Directly Through Containers

Use of the Agilent Vaya Raman handheld spectrometer for the identification of oligonucleotide starting materials, phosphoramidites, directly through amber bottles.

  • Application Notes
  • 770.37 KB

Quantification and Identity Testing of Soft Gel Capsules using Transmission Raman Spectroscopy

This study presents an efficient and cost saving analytical technique requiring no sample preparation

  • Application Notes
  • 638.73 KB

Solutions for Accelerated Raw Materials Identification

This e-book describes how a through-container handheld Raman instrument can be used to reduce the turn around time and cost of pharmaceutical raw material quality control

  • Primers
  • 3.11 MB

Detection of Hazardous Narcotics and New Psychoactive Substances (NPS) with Agilent Resolve—a Handheld SORS System

Use of Resolve allows the examination a maximum range of packages or containers for indications of hazardous materials before disturbing, opening, or taking a sample.

  • Application Notes
  • 1.67 MB
Featured Videos

Benefits of Transmission Raman Spectroscopy over Standard Operating Processes

  • 00:02:51

Specialist Search Operation using the Resolve Raman Analyzer

  • 00:01:45

Increase Your Reach, Not Your Costs with the Agilent Vaya Handheld Raman Spectrometer

  • 00:02:08

EOD— Tackling a Vehicle-Borne Improvised Explosive Device with the Resolve Raman Analyzer

  • 00:03:17
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Featured News

AstraZeneca Webinar Discusses Extended Uniformity of Dosage Unit Testing of Pharmaceutical Tablets Using TRS

Transmission Raman spectroscopy (TRS) is non-destructive and high throughput, so can be applied to extended uniformity of dosage unit testing and enhanced control strategies aiming at real-time release for batch and continuous operations. Hear Anders Sparén, Associate Principal Scientist at AstraZeneca, present his team’s work showing why TRS is an ideal technique for the assessment of assay, uniformity of dosage unit, and polymorphs in tablets and capsules.

  • 20 Mar 2023

Agilent Deploys Next Generation Explosive Detection System at London Heathrow Airport

Agilent Technologies announces the deployment of the next generation of alarm resolution technology for checkpoints throughout London Heathrow airport, delivering advanced security and efficiency. Agile to future threats, the Insight200M from Agilent ensures increased safety on planes while improving passenger experience at airports.

  • 29 Nov 2022

Agilent Vaya Raman Spectrometer Receives My Green Lab’s ACT Certification Label

The Agilent Vaya Raman system has been certified with the ACT label in the EU, UK, and US. This clear, third-party verified information about the system’s environmental impact makes it easy for laboratories to choose products that help them achieve their sustainability goals.

  • 30 Oct 2022
Featured Training & Events

Boost Productivity and Eliminate Waste in Raw Material ID

Raw material identification (RMID) is a regulatory-enforced step in drug manufacturing for pharmaceutical and biopharmaceutical organizations.
Webinar/Training

Implementing Transmission Raman for Fast Content Uniformity Testing – from Feasibility Evaluation to a Validated Release Method

The webinar highlights the approach that led to the implementation of transmission Raman spectroscopy for content uniformity testing at a pharmaceutical company. The webinar also discusses the reasons for using transmission Raman spectroscopy for content uniformity and how it works in conjunction with established liquid chromatography (LC) methods.
Webinar/Training

Molecular Spectroscopy Webinar Curriculum

Molecular Spectroscopy Webinar Curriculum includes UV-Vis, UV-Vis-NIR, fluorescence, handheld and benchtop FTIR, and Raman systems for high performance and flexibility
Webinar/Training

Spectroscopy Digital Workshops & Bootcamps

Hone your lab skills, outside the lab, with our live, interactive series of virtual workshops and software bootcamps! Learn about the latest in software solutions for Spectroscopy, discuss the entire analytical process from method development to data analysis, and participate in live analytical runs with our experts. We hope these will prepare you for future hands-on events in the future.
Webinar/Training
Featured References
  1. View all spatially offset Raman spectroscopy (SORS) and transmission Raman spectroscopy (TRS) peer-reviewed publications Learn More

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