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Cell Analysis Technology News and Information

Measure what matters – Agilent live-cell metabolism solutions

With over 20,000 genes, 200,000 proteins and thousands of pathways, you can't measure everything in a cell at once, but you can measure the energy that drives them.

Agilent offers cell analysis solutions that detect discrete changes in cellular bioenergetics in real-time. Real-time cell measurements provide a clear window into the critical functions driving cell signaling, proliferation, activation, toxicity and biosynthesis. Move beyond analyzing what your cells are to reveal a clearer picture of what they do.

Discover the drivers of cell fate, function & fitness

Mitochondrial function and glycolysis play critical roles in a variety of cellular processes. Discover how real-time, live cell analysis can provide a complete picture of what's driving your cells' phenotype and function.

Cancer - discover drivers, dependencies and liabilities of cancer cell biology

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Cancer cells reprogram their metabolism in order to generate the energy and building blocks they need to proliferate. Agilent Seahorse XF technology provides a window into the Warburg effect, fuel usage and other events that drive tumor cell biology.

Immunology – unlock immunometabolism, the driver of immune cell function

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Immunometabolism has emerged as a crucial component to understand the connection between metabolic pathways and immune responses. Seahorse XF Technology enables researchers to understand and perturb immune activation and response in real-time through metabolic measurements.

Drug discovery – expand your pipeline, target novel metabolic pathways

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From target identification and validation, to toxicology, and mechanism of action, being able to collect direct measurements of cell and energy metabolism will allow you to expand your drug discovery pipeline by targeting metabolic pathways, assessing compounds for mitochondrial toxicity, and better understanding their mechanisms.

Immunotherapy – tune the drivers of immune cell fate, fitness and potency

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Developing immune cell therapies requires an in depth understanding of immune cell function. This requires key technologies from high-efficiency gene editing to assessment of real-time cell function, phenotype, and fate. Discover Agilent's tool bench of solutions that will enable you to develop potent and safe therapeutics.

Other research areas

Flexible solutions for real-time, live cell metabolic analysis

Agilent offers two platforms for studying live cell metabolism. The Seahorse XF platform is a label-free, end-to-end, integrated platform that seamlessly combines instrument, sensor cartridge, assay kits and software to deliver quantitative cell metabolic data with real-time compound exposure kinetics. The MitoXpress and pH-Xtra assays are soluble sensor reagents for TR-F enabled plate-readers.

Seahorse kit
Seahorse kit

Educational & planning resources

Learn how to run an XF assay

The Seahorse XF Assay Learning Center provides protocols, techniques and resources aligned to each step of the XF workflow to ensure optimal assay performance and results. The XF Assay Learning Center has been recently updated to reference the new Seahorse XF Real-Time ATP Rate Assay for performing initial cell characterization.

Get started
Seahorse kit

Getting started

Seahorse XF Assay learning center

The XF Assay Learning Center provides the most up-to-date information on protocols and procedures for preparing, running, and analyzing an XF assay.

Cell analysis selection guide

Understanding which Agilent cell metabolism assay best suits your biological questions, workflow, and throughput goals.

Seahorse XF instruments selection guide

All Seahorse XF instruments analyze mitochondrial respiration and glycolysis in live cells, generating data in just minutes.

How Seahorse analyzers work

Seahorse XF technology uses solid-state sensors to simultaneously measure both oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in every well.

Make Seahorse part of your next NIH grant application

Seahorse XF is a standard for measuring functional cell metabolism that can be leveraged to support the diverse research aims within grant-funded research projects. Learn from experts and existing users how to leverage Seahorse XF to strengthen your NIH grant application.

Videos

Cell Analysis videos

Demonstrating how the XF Technology works and how it is being used.

Cell Analysis webinars

Focusing on a wide range of topics.

Publication database

Cell Analysis Publications Database

Browse the full list of publications using Agilent Cell Analysis data.

Unique insights delivered by validated, end-to-end metabolic assays

Agilent has many standard assays built on oxygen and pH sensor technologies to help you to address your research needs.

Community Center

Cell analysis community

Agilent community for Seahorse and Soluble Sensors:

Core facilities with Seahorse XF Research Services

Cell analysis travel awards for graduate students and young investigators

Seahorse grant expeditor package can simplify your grant application process

Worldwide Technical Support

E-mail:

cellanalysis.support@agilent.com

US and Canada

1-800-227-9970; select option 3 then 8

Europe

UK: 0800 096 7632

Germany: 0800 180 66 78

Netherlands: 0800 022 7243

Other EU: +45 3136 9878