Small molecule liquid chromatography (LC) columns, or high performance liquid chromatography (HPLC) columns, separate your analytes of interest in a wide range of compounds.
Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.
Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industrys highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.
The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.
When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the worlds largest chromatography supplier.
The Agilent ZORBAX family offers all advantages of totally porous particle columns such as increased retention, loadability and resistance to sample solvents.
Featured Customer Testimonials
Dr. Stefan Bieber
Managing Director, AFIN-TS GmbH
Our SFC method development strategy always includes stationary phases of Agilent Technologies, Inc. We strongly appreciate the robustness of polar ZORBAX and Poroshell phases, such as ZORBAX Rx-SIL and Poroshell 120 HILIC. They exhibit good selectivity and high separation performance, which is key for successful and efficient method development in SFC. The broad spectrum of available column dimensions has great advantage for the optimization of separations and allows us to adjust the column dimension to obtain the most efficient separations.
Agilent announced a highly-anticipated, complete workflow solution for targeted per- and polyfluoroalkyl substances (PFAS) analysis using the United States (US) Environmental Protection Agency (EPA) Method 1633 (3rd draft). EPA Draft Method 1633 currently analyzes 40 PFAS compounds in wastewater and soil and is a complex and labor-intensive method, relying on multiple sample preparation and analysis steps. Success in running the technique depends on careful sample handling and the appropriate sample preparation supplies and instrumentation.
Agilent acquires Polymer Standards Service (PSS), broadening offerings for gel permeation chromatography (GPC) and size exclusion chromatography (SEC) polymer analysis. The acquisition expands Agilent’s portfolio and offerings for the analysis of natural and synthetic polymers.
Per- and polyfluoroalkyl substances (PFAS) are a large group of anthropogenic chemicals that have been applied in industrial, commercial, and domestic products since the 1950s. Because of their toxicity, persistence, and bioaccumulation potential, PFAS have become global environmental pollutants. Besides the environment, the food chain represents another source of exposure, and the risk related to the presence of PFAS in foods has become of increased interest. Whole milk, infant formula, and ingredients used in infant formula production represent important foodstuffs that require sensitive methods with reporting limits at low parts per billion levels or lower for multiple PFAS. This article summarizes optimization experiments and validation of a complete workflow, including sample preparation and a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for determination of sixteen priority PFAS analytes listed by the U.S. Food and Drug Administration (FDA).