
1260 Infinity II SFC System
The broad power range gives you an extended application reach and the use of food-grade carbon dioxide (CO2) guarantees lowest operating costs and a fast return on investment. Detection capabilities can be expanded by adding an Agilent mass spectrometer, 1260 Infinity II Evaporative Light Scattering Detector, or a SIM flame ionization detector.
- Application Specific HPLC Systems
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Product Details
- Broad power range supports pressures up to 600 bar at flow rates up to 5 mL/min for extended application reach
- Orthogonal technique to reversed-phase LC minimizes risk of peaks going unseen
- Intuitive SFC system brings ease of use and speed to normal-phase chromatography
- Wide range of injection volumes from 0.1 to 90 µL enables flexible injection without changing sample loops
- Innovative Feed Injection technology guarantees outstanding injection precision and LC-like reproducibility
- Multisampler handles up to 6,144 samples for high-throughput applications
- Compatibility with wide range of Agilent mass spectrometers adds SFC/MS capability
- Upgrade options for existing 1100, 1200, or 1260 LC equipment provides for maximum convenience and effective budgeting
- Low solvent consumption and less waste gives you true green chemistry
- Use of beverage-grade CO2 achieves 10 to 15 times lower operating costs
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- Mobile Phase Delivery
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1260 Infinity II SFC Binary Pump
600 bar and 5 mL/min power range for extended SFC and SFC/MS application reach.
- Sample Introduction
- Column Handling
- Detection
- Recommended Accessories
- Application Notes
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Detection of Low-Level Impurities in Salbutamol Using the Agilent 1260 Infinity II SFC System with VWD
The objective of this application note is to demonstrate a competitive trace analysis of impurities in the API salbutamol sulfate using the combination of the Agilent 1260 Infinity II SFC System with an Agilent 1290 Infinity II Variable Wavelength Detector (VWD).
- Application Notes
- English
- 03 Sep 2021
- 570.92 KB
Orthogonal Separation of Pharmaceutical Impurities
The Agilent 1260 Infinity II SFC/UHPLC Hybrid System with an 1260 Infinity II VWD is used to determine pharmaceutical low-level impurities in an API.
- Application Notes
- English
- 19 Dec 2019
- 483.76 KB
Improved Sensitivity for Low-Level Impurity Detection with the Agilent 1260 Infinity II SFC System
This application note demonstrates the optimum field of application for the detection of low-level impurities in an API with the Agilent 1260 Infinity II VWD.
- Application Notes
- English
- 27 Nov 2019
- 573.68 KB
Separation of Highly Polar Compounds by SFC With Detection by Q-TOF LC/MS
Separation of Highly Polar Compounds by SFC With Detection by Accurate-Mass Q-TOF LC/MS and Identification With Database and Library Searches
- Application Notes
- English
- 25 Jul 2019
- 3.21 MB
Easy Access to Rapid Chiral SFC Method Development for Non-Chromatographers
Easy access chiral supercritical fluid chromatography (SFC) method development system for non‑chromatographers, to attain chiral SFC method development requirements.
- Application Notes
- English
- 10 Jan 2019
- 1.97 MB
Method Development Using Method Scouting Wizard on the Agilent 1260 Infinity Analytical SFC System with Time-of-Flight Mass Spectrometric Detection
Describes the use of the Agilent ChemStation Method Scouting Wizard in method development to separate and detect active compounds using SFC and TOF MS.
- Application Notes
- English
- 05 Oct 2018
- 1.17 MB
Application Compendium Supercritical Fluid Chromatography
This compendium demonstrates the application reach of the Agilent InfinityLab SFC Solutions providing examples from pharma, biopharma, food, forensics and chemicals.
- Application Notes
- English
- 29 Nov 2017
- 12.37 MB
Development of a method for the chiral separation of D/L-Amphetamine
Method development for the separation and quantitation of D-, and L-Amphetamine enantiomers
- Application Notes
- English
- 11 Oct 2017
- 988.48 KB
Chiral Multicolumn Method Development on the 1260 Infinity II Analytical SFC System
Development of a chiral separation method on the Agilent 1260 Infinity II Analytical SFC system using the Agilent ChemStation Method Scouting Wizard
- Application Notes
- English
- 11 Oct 2017
- 1.84 MB
- Brochures
- Technical Overviews
- Firmware
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- Supplemental Information
- User Manuals
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