HPLC & UHPLC Systems

Discover HPLC and UHPLC Instruments Suitable for Every Application

Explore our reliable HPLC and UHPLC systems. Great scientific breakthroughs and QA/QC routine analysis that meet productivity goals need dependable chromatography instruments.

Our wide range of affordable and advanced Agilent HPLC and UHPLC instruments deliver the performance, reliability, and robustness you need for the highest confidence in your daily results. But confidence isn’t enough. Improving productivity, increasing efficiency, and maximizing return on investment are key to your scientific excellence and success. Discover the ideal Agilent HPLC systems for your laboratory and analytical scientists needs.

LC Resources

HPLC Fundamentals and FAQs

Infinity III LC Series: FAQs Answered

Preparative HPLC Basics and FAQs

New InfinityLab Assist Technology

Upgrade Existing HPLC/UHPLC Systems

HPLC Advisor App

PFAS Analysis and Workflows

Featured Literature

Span the Spectrum of Bio LC

Discover the new Agilent InfinityLab Bio LC Solutions, a wide portfolio designed to help you overcome your bioanalytical challenges.

Brochures
2.57 MB

Two Dimensions for Ultimate Separation Power

Do you need an extra level of resolution and confidence in your analyses? Discover our powerful solutions for two-dimensional liquid chromatography (2D-LC).

Brochures
3.68 MB

Online Monitoring of a Heterogenic Liquid/Liquid Reaction

This application note will describe the combination of the Agilent 1260 Infinity II Online LC with the Mettler Toledo EasySampler 1210, using the Snapdragon Chemistry’s SRS module, for monitoring of heterogenic reactions.

Application Notes
357.70 KB

Purify Your Samples with Maximum Flexibility

Agilent InfinityLab LC Purification Solutions offer high-performance instrumentation, columns, software, and services for analytical- to preparative-scale workflows.

Brochures
1.95 MB

Featured News

Infinity III LC with Pro iQ Mass Detector has achieved Platinum-level My Green Lab® ACT® Ecolabel certification

At Agilent, sustainability is a responsibility woven into how we innovate. We're proud to share that the Infinity III LC with Pro iQ Mass Detector has achieved Platinum-level My Green Lab® ACT® Ecolabel certification — providing labs with clear, third-party verified sustainability data to support informed purchasing decisions. This certification provides credible information on our product’s sustainability attributes, including material content, product lifetime, recycled packaging content, and end-of-life considerations, all of which were deliberately considered during our design process. For Agilent, the ACT Ecolabel establishes a transparent baseline and a consistent framework for continuous improvement — helping us measure, communicate, and reduce the environmental impact of our products across their lifecycle.

11 Jun 2026

2026 Scientists’ Choice Award Winner: Pro iQ Series Mass Detector

This year's award for Best New Analytical Science Product of 2025, voted for by scientists around the world, was a tie and is jointly awarded to two products: the Agilent InfinityLab Pro iQ Series mass detector and the Merck TLC Explorer. Upon receiving the award, Shane Tichy, Associate Vice President, LC/MS R&D, Agilent, shared: “We’re honored to receive the SelectScience Award for the Pro iQ Series mass detector, an achievement that highlights Agilent’s leadership in analytical innovation. This recognition reflects our commitment to customers, redefining performance through superior sensitivity, exceptional reliability, and ease of use, all within a sustainable footprint. Agilent remains dedicated to delivering cutting-edge solutions that accelerate progress and unlock new possibilities in science.”

10 Jun 2026

Start-to-Finish Workflows for PFAS Analysis: Meet the Challenges of a Regulated Landscape

Get the answers to FAQs about per- and polyfluoroalkyl substances (PFAS). Plus, learn how Sanexen Environmental Services have optimized their end-to-end PFAS workflows. Also, listen to experts at Weck Laboratories address the challenges of low-level quantitation when analyzing PFAS.

15 Jan 2024

0 product selected.

Clear All