GenetiSure Cyto CGH & CGH+SNP Microarrays
Intended for use by cytogenetic research and clinical laboratories, this microarray is focused on disease-associated regions linked to developmental delay, intellectual disability, neuropsychiatric disorders, congenital anomalies or dysmorphic features. The 180K CGH array provides high resolution CN down to exon level. The 180K CGH+SNP array provides genome wide CN and high resolution LOH down to 2.5 Mb. And the 8x60K offers a great compromise between coverage, throughput and cost per sample.
- Human Microarrays
Product Details
- Designed to meet cost, throughput, and resolution needs for any laboratory performing pre or postnatal research
- Increased resolution in clinically-relevant target regions sourced from ClinGen, OMIM, and DECIPHER databases, genome-wide backbone with increased resolution in telomeres
- Excellent option for both reflex and confirmatory testing in conjunction with other technologies such as next generation sequencing (NGS)
- All designs include spike-in probes for sample tracking
- Free space on the array allows for easy customization to integrate lab-specific gene/region of interest
- 180K CGH array design provides exon-level coverage in a selected set of genes
- 180K CGH+SNP array design includes High-resolution SNP probes, exceeding new ACMG guidelines, for analysis of absence of heterozygosity (AOH) genome-wide in a single experiment
- 60K CGH array format offers a great compromise between coverage, throughput, and cost per sample
- A complete workflow, provided by a single supplier, benefits with inventory control, one-stop service calls and bulk purchasing efficiencies
- Probes are annotated against NCBI Build 38 (UCSC GRCh38, Dec. 2013)
- Application Notes
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Use of Spike-ins for Sample Tracking in Agilent Array CGH
This application note describes the use of spike-ns for sample tracking in Agilent Array CGH. Analysis is performed leveraging CytoGenomics software.
- Application Notes
- English
- 16 Mar 2016
- 835.11 KB
- Brochures
- User Manuals
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Quick Reference Guide for 8x Arrays - Oligonucleotide Array-Based CGH for Genomic DNA
A quick reference guide for processing 8-pack aCGH microarrays using enzymatic labeling of gDNA from blood, cells, or tissues.
- User Manuals
- English
- 01 Apr 2020
- 164.20 KB
Quick Reference Guide for 4x Arrays - Oligonucleotide Array-Based CGH for Genomic DNA
A quick reference guide for processing 4-pack aCGH microarrays using enzymatic labeling of gDNA from blood, cells, or tissues.
- User Manuals
- English
- 01 Apr 2020
- 163.88 KB
Oligonucleotide aCGH for gDNA Analysis - Enzymatic Labeling For Blood, Cells, or Tissues (with a High Throughput option)
Oligonucleotide Array-Based CGH for Genomic DNA Analysis - Enzymatic Labeling For Blood, Cells, or Tissues (with a High Throughput option) Protocol
- User Manuals
- English
- 04 Mar 2020
- 4.63 MB
Oligonucleotide Array-Based CGH for Genomics DNA Analysis- Bravo Automated Liquid Handling Platform with Enzymatic and ULS Labeling Protocol 2.3
Oligonucleotide Array-Based CGH for Genomics DNA Analysis- Bravo Automated Liquid Handling Platform with Enzymatic and ULS Labeling Protocol 2.3
- User Manuals
- English
- 25 Aug 2015
- 3.09 MB
- Publications
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- Chromosomal microarray analysis of Bulgarian patients with epilepsy and intellectual disability. Peycheva V, Kamenarova K, Ivanova N, Stamatov D, Avdjieva-Tzavella D, Alexandrova I, Zhelyazkova S, Pacheva I, Dimova P, Ivanov I, Litvinenko I, Bozhinova V, Tournev I, Simeonov E, Mitev V, Jordanova A, Kaneva, R. Gene. 2018 Aug 15;667:45-55. doi: 10.1016/j.gene.2018.05.015. Epub 2018 May 9. [Application: Postnatal] Learn More
- Pinto D et al. Comprehensive assessment of array-based platforms and calling algorithms for detection of copy number variants. Nat Biotechnol. 2011 May 8;29(6):512-20. doi: 10.1038/nbt.1852 [Application: General] Learn More
- Alesi V et al. Easychip 8x15k: A New Tool for Detecting Chromosome Anomalies in Low Risk Pregnancies, Supporting and Integrating Standard Karyotype J Genet Syndr Gene Ther 7: 277. doi:10.4172/2157-7412.1000277 [Application: Prenatal] Learn More
- Chau MHK et al. Characteristics and mode of inheritance of pathogenic copy number variants in prenatal diagnosis. Am J Obstet Gynecol. 2019 Nov;221(5):493.e1-493.e11. doi: 10.1016/j.ajog.2019.06.007. Epub 2019 Jun 14. [Application: Prenatal] Learn More
- Ribeiro et al. Upper aerodigestive tract carcinoma: Development of a (epi)genomic predictive model for recurrence and metastasis. Oncol Lett. 2020 May;19(5):3459-3468. doi: 10.3892/ol.2020.11459. Epub 2020 Mar 12 [Application: Cancer] Learn More
- Kaur et al. Clinical impact of chromothriptic complex chromosomal rearrangements in newly diagnosed multiple myeloma. Leuk Res. 2019 Jan;76:58-64. doi: 10.1016/j.leukres.2018.12.005 [Application: Cancer] Learn More
Microrray Quality Information
Lot quality data and product identification information for microarrays manufactured after May 22, 2013.
SureDesign
A web-based application that harnesses the flexibility of SurePrint oligo manufacturing technology.