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Wide Pore LC Columns for Intact Protein & Subunit Analysis

Agilent offers a number of wide pore reversed-phase columns. From superficially porous, silica-based AdvanceBio RP mAb to totally porous, polymer-based PLRP-S, there is a column solution for every intact or subunit protein separation.

Intact & Subunit Analysis

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Featured Tools

Bio HPLC Columns eSelector Tools

Intuitive process to help you select the right chromatography column for your biopharmaceutical applications.

Preparative HPLC Scaling Calculator

Scale between analytical and prep methods; calculate column capacity, # of injections, run time & mobile phase use.

HPLC & LC Column Selector Tool

A series of tools to help you navigate to the best HPLC column choice for your application.

Featured Literature

N-Glycan Analysis: Better Together

Push your Glycoprotein analysis to new levels of performance.

Glycan Standard Structures

Catalog of glycan standards and libraries, complete with quick links to easily get more details for each online.

Agilent Biocolumns - Critical Quality Attributes - Application Compendium

Critical Quality Attributes application compendium

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Featured News

Agilent Wins Multiple 2022 Scientists' Choice Awards

Agilent received two 2022 Scientists’ Choice Awards for Drug Discovery & Development, Virtual Event of the Year and Innovative Content of the Year, at the SLAS2022 International Conference & Exhibition on February 7th, 2022. The Scientists’ Choice Awards recognize the world’s most innovative and effective analytical science technologies and communications.

The Importance of Glycan Analysis and Characterization for Biopharma

Professor Michael Butler, head of the National Institute for Bioprocessing Research and Training (NIBRT) Cell Technology Group (CTG), explains that the characterisation and analysis of glycans is important for the biopharma sector as it can help in the development of therapeutic agents, such as monoclonal antibodies and other recombinant proteins. These are used in therapies in a range of serious conditions including cancer, inflammatory diseases, and cardiovascular diseases. The mechanism of action depends upon their strong affinity to molecular targets associated with disease.

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