AdvanceBio Spin Columns address the need for efficient sample preparation of proteins or oligonucleotides under aqueous conditions, preserving native structure with suitable ionic strength and pH. Users can easily and quickly remove excess salts or undesired small molecules from their sample matrix or exchange the sample matrix between different buffer conditions. These gel-filtration-based spin columns are available in analytical and semipreparative scale columns for single samples, as well as 96-sample plates for high-throughput settings.
爱尔兰国家生物工艺研究与培训研究所 (National Institute for Bioprocessing Research and Training, NIBRT) 细胞技术小组 (CTG) 负责人 Michael Butler 教授解释说,多聚糖的表征和分析对于生物制药行业很重要,因为它可以帮助开发治疗药物,例如单克隆抗体和其他重组蛋白。这些药物可用于治疗一系列严重疾病,包括癌症、炎症性疾病和心血管疾病。它们的作用机制取决于它们对与疾病相关的分子靶标的强亲和力。