ZORBAX Eclipse XDB

Eclipse XDB columns can be used for initial method development at low pH (2–3) and will provide high resolution and excellent peak shape of all types of compounds. The same column can be used for method development in the mid pH (6–8) region. In the mid pH region residual silanols are more active and tailing interactions are more likely. To overcome these interactions, Eclipse XDB columns are extra densely bonded and double endcapped through a proprietary process to cover as many active silanols at possible. The result is superior peak shape of basic compounds from pH 2 9.

Eclipse XDB columns are available in C18, C8, Phenyl and CN bonded phases for selectivity optimization of most separations with StableBond, Bonus-RP and Extend-C18 available as additional selectivity choices. Eclipse XDB columns are available in particle sizes ranging from 1.8 µm to 7 µm RRHT to Prep. Rapid Resolution HT (RRHT) columns provide the fastest analysis times and the highest resolution in a new wider range of column dimensions supporting high-pressure use.

Bonded Phase	Pore Size	Surface Area	Temp. Limits	pH Range*	Endcapped	Carbon Load	USP Designation
ZORBAX Eclipse XDB-C18	80Å	180 m²/g	60 °C	2.0 - 9.0	Double	10%	L1
ZORBAX Eclipse XDB-C8	80Å	180 m²/g	60 °C	2.0 - 9.0	Double	7.60%	L7
ZORBAX Eclipse XDB-Phenyl	80Å	180 m²/g	60 °C	2.0 - 9.0	Double	7.20%	L11
ZORBAX Eclipse XDB-CN	80Å	180 m²/g	60 °C	2.0 - 8.0	Double	4.30%	L10

Specifications represent typical values only.

*Eclipse XDB columns are designed for operation over a wide pH range. At pH 6–9, highest columns stability for all silica based columns is achieved by operating at temperatures < 40 °C and using low buffer concentrations in the range of 0.01–0.02 M.