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Cancer Research

Cancer Research

Measure cancer cell metabolism to exploit cancer liabilities

Metabolic reprogramming is an emerging hallmark of cancer that can provide insight into cancer dependencies and therapeutic targets. Conventional views commonly assume that cancer cells rely on upregulated glycolysis for proliferation, often characterized as the Warburg effect. However, the metabolic phenotypes of cancer cells are highly variable, with some cancer cells relying on oxidative metabolism for unregulated proliferation and survival. Discover how to expose and exploit these metabolic vulnerabilities using functional live cell metabolism in your cancer research.

Agilent Cell Analysis technology provides unique capabilities to reveal metabolic vulnerabilities, including:

  • Simultaneous measurements of glycolysis and oxidative phosphorylation for metabolic phenotyping providing a complete window into metabolic dependencies
  • Real-time, kinetic analysis to reveal dynamic cancer cell strategies
  • Functional measurements for identification and validation of druggable targets

Download our brochure for research and application highlights of how Agilent Cell Analysis measurements can be applied to cancer research.

Visit the Agilent Cell Analysis Publications Database or Cell Reference Database to search for publications relevant to your research.

View Agilent Cell Analysis webinars on-demand page to discover applications in cancer research.