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Be Agilent Sure in Peptide Mapping

Be Agilent Sure in Your Peptide Mapping and PTM Analysis

Thorough peptide mapping is critical to fully understanding your protein. You must also identify and quantify degradation products and post-translational modifications (PTMs) that can impact protein activity. Innovative Agilent samples-to-answers solutions deliver accurate, reproducible results and streamline your workflow.

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Peptide mapping and PTM identification and quantitation are vital to creating high-quality biotherapeutics. Agilent instruments, columns, databases, methods, and more ensure that every element of your peptide-mapping workflow performs as it should. You’ll be able to do less—and get more done—without sacrificing precision.

Click each icon to learn how Agilent can help at every step of your peptide mapping and PTM analysis workflow.







The Agilent AssayMAP Bravo platform combines automated liquid handling with work-saving enhancements for precise, reproducible peptide analysis.

Take advantage of the reliable, high-performance Agilent 1290 Infinity II LC system, and get higher peak capacity for challenging separations with the 2D-LC solution.

Agilent AdvanceBio Peptide Mapping columns provide high-resolution peptide maps for protein identification and PTM determination.

Whether you are performing routine sequence confirmation, or faced with hard-to-detect peptides, you can count on the Agilent 6545XT AdvanceBio LC/Q-TOF system.

Advanced data mining and processing tools in the Agilent MassHunter software suite help you quickly and accurately extract all available information from your samples. What’s more, Agilent MassHunter BioConfirm software can identify and confirm PTMs before you start expensive testing.

MassHunter Walkup transforms mass spectrometry from a limited-access service into a tool that anyone can use.

Agilent CrossLab service plans care for your entire laboratory with rapid onsite support, multivendor instrument service, remote instrument diagnostics, and more. From maintenance and repairs… to compliance… to relocation… our expert engineers provide insights that can improve efficiency for one instrument, or an entire lab.

Everything you need to streamline peptide mapping and PTM analysis


Looking for detailed information on new techniques or technologies? Our wide range of application notes, videos, on-demand webinars, and other resources can help you achieve more accurate, reproducible results.

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Featured webinar


A Fast and Sensitive Workflow for In-Depth Peptide Mapping and PTM Analysis

  • Learn how our integrated peptide-mapping workflow automates and streamlines this complex process.
  • See how a new LC/Q-TOF acquisition method—iterative MS/MS—makes method optimization easy and improves sensitivity for low-abundant peptides.
  • Discover how to simplify identification and quantification of PTM peptides.
Register now

Featured video

From Sample Preparation to Data Analysis: Agilent Biopharma Workflow

Characterizing proteins requires multiple approaches to accessing varying levels of information. Learn how sample preparation, LC/MS, and software innovations can help you meet your protein characterization challenges.

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Featured application notes

application note

Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies

Using Agilent 6545XT AdvanceBio LC/Q-TOF and BioConfirm Software

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application note

In-depth Peptide Mapping with Iterative MS/MS Acquisition on the Agilent 6545XT AdvanceBio LC/Q‑TOF

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