Quickly analyze underivatized amino acids by LC/MS

Now you can analyze amino acids and other cell culture metabolites with a single method: HILIC LC separation with MS detection.

Agilent AdvanceBio MS Spent Media columns are ideal for normal phase separation of amino acids and small, polar metabolites in cell culture media. They feature a zwitterionic phase bonded onto superficially porous silica particles, enabling fast, efficient, and reproducible separations of small, charged molecules. You can also count on:

• Simplicity: Eliminate sample derivatization—
  and the need for baseline resolution with MS detection
• Performance: PEEK-lined stainless steel columns ensure excellent peak shape and recovery of challenging ionic metabolites
• Sensitivity: Engineered with MS-friendly mobile phases
• Flexibility: Compatible with HPLC and UHPLC systems

Visit our Critical Quality Attributes page to learn more about enhancing your accuracy and speed.

Spent Media Analysis Productivity Kit

Simplify your LC/MS analysis of amino acids and other small metabolites in spent cell culture media.

Brochure: Agilent AdvanceBio Workflows for Spent Media Analysis

Application note: Analysis of Underivatized Amino Acids by LC/MS for Bioreactor Cell Culture Monitoring