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This application note demonstrates separation characteristics of a series of divinylbenzene-based PLOT columns. With the incorporation of functional groups, the porous polymer’s selectivity and polarity used as a stationary phase can be adjusted to tailor for different applications. Selectivity tuning is demonstrated as viable to alter the overall separation characteristic and offer separation that cannot be achieved with a single column. Improvements in porous polymers manufacturing have led to columns with higher stability, robustness, inertness, and reduced spiking.
