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Chiral LC Columns

Fast, reproducible separation of enantiomers in all common LC modes

Agilent offers a modern portfolio of chiral columns that allow fast, reproducible separation of enantiomers in all common high-performance liquid chromatography (HPLC) modes. Immobilized chiral selectors offer a broad range of enantioselectivity making the columns ideal for chiral method screening.

Chiral LC Columns

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HPLC & LC Column Selector Tool

A series of tools to help you navigate to the best HPLC column choice for your application.

Preparative HPLC Scaling Calculator

Scale between analytical and prep methods; calculate column capacity, # of injections, run time & mobile phase use.

Bio HPLC Columns eSelector Tools

Intuitive process to help you select the right chromatography column for your biopharmaceutical applications.

Essential Supplies Guide for InfinityLab LC Series Instruments

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Featured Customer Testimonials

Dr. Stefan Bieber

Managing Director, AFIN-TS GmbH

Our SFC method development strategy always includes stationary phases of Agilent Technologies, Inc. We strongly appreciate the robustness of polar ZORBAX and Poroshell phases, such as ZORBAX Rx-SIL and Poroshell 120 HILIC. They exhibit good selectivity and high separation performance, which is key for successful and efficient method development in SFC. The broad spectrum of available column dimensions has great advantage for the optimization of ...

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Sébastien Leclerc

Analytical Chemist, SANEXEN Environmental Services, Inc.

The partnership with Agilent extends way beyond the initial purchase or initial installation. They provide the consumables and also the expertise.

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Featured Videos

Scale Up to the Fast Lane

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InfinityLab Poroshell 120 Preparative LC Columns

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Featured News

Meet the New Altura Family of HPLC Columns

Altura columns feature Agilent's innovative Ultra Inert technology. The advanced coating blocks active metal sites, ensuring an inert flow path while maintaining the strength, pressure tolerance, and consistency of a traditional stainless steel HPLC column. Altura columns unlock the true separation potential of the stationary phase. Experience superior chromatographic performance, faster equilibration, and enhanced sensitivity for your most challenging metal-sensitive analytes.

  • 01 Oct 2025

Develop Fast Purification Methods for Natural Products

A fast and simple purification method for withaferin A in ashwagandha extract was successfully developed using an Agilent InfinityLab Poroshell 120 SB-C18 preparative HPLC column. The InfinityLab Poroshell 120 column provided better resolution and a 45% decrease in run time over a traditional preparative column. The performance benefits of InfinityLab Poroshell preparative columns, especially at high flow rates, align well with the needs of pharmaceutical discovery laboratories and other high-throughput environments.

  • 26 Feb 2024

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