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Top-DNA Well-Plate Tubes

Top-DNA Well-Plate Tubes

Top-DNA Well-Plate Tubes

TOP-DNA removes interfering salts, incomplete synthesis products, and other impurities from synthetic DNA oligonucleotides - in a few simple steps. TOP-DNA purifies oligonucleotides of up to 150-mer in length and from 200 nmol to 1 µmol. TOP-DNA can also be used for sample preparation before HPLC purification.

TOP-DNA can be used for the purification of synthetic oligos, regardless of their length. You will not need separate methods for short and long products. The unique sorbent allows detritylation while oligos are bound in the cartridge. Base deprotection can be done with the faster AMA method (1:1 mixture of ammonium hydroxide and methylamine, 40 wt % solution in water), saving valuable time and increasing throughput.

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