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Solid Phase Extraction (SPE) Cartridges, Well Plates, Sorbents

Solid Phase Extraction (SPE) is a sample preparation technique with principles similar to those of high-performance liquid chromatography (HPLC) for selective adsorption of analytes or interferences from complex matrices. SPE extraction is used for sample clean-up and analyte concentration preceding liquid chromatography (LC), gas chromatography (GC), ion chromatography and other techniques. SPE is considered a cost-effective alternative to or replacement for liquid-liquid extraction (productivity, solvent, waste).

The advantages of SPE versus liquid-liquid extraction include improved throughput, decreased organic solvent usage and waste generation, higher and more reproducible recoveries, cleaner extracts, no emulsions, tunable selectivity and automation.

Typical applications of SPE include sample clean-up, trace enrichment, desalting, solvent exchange and sample preservation and storage.

SPE usage is accelerating in combinatorial synthesis and high-throughput LC-MS analysis. Increase in overall LC-MS usage improves instrument uptime. SPE decreases organic solvents and waste.

Agilent offers SPE products in various polarities and chemistries to achieve consistent sample processing. A broad selection of Bond Elut sorbents are available in cartridge and well plate formats and as bulk sorbents. Frits, adapter caps, empty cartridges for custom packing, and online SPE cartridges can also be purchased. Bulk packaging of SPE products provides a cost-effective solution for high-throughput workflows.

Solid Phase Extraction (SPE)

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Featured Tools

Captiva Syringe Filter Selector Tool

The Captiva Syringe Filter selector tool helps you find the best syringe filter to suit your sample prep needs.

Solid Phase Extraction (SPE) Selector Tool

The SPE Selector Tool helps find the best SPE based on your application, SPE format, sample volume and bed mass.

QuEChERS Selector Tool

QuEChERS eSelector provides extraction and dispersive kit recommendations for pesticides in fruit and vegetables.

Featured Customer Testimonials

Raúl Vigas

CEO, J·Vigas

The SPME Arrow – Intuvo GC – MS/MS system incorporates maximum precision coupled with a speed that is not achieved with any other technology. According to the studies of J·Vigas, there is no other equipment on the current market for the analysis of TCA in wine stoppers that gives such reliable results in 5 minutes.

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Featured News

Agilent's Bond Elut PFAS WAX Named 2023 Top Product by Environment+Energy Leader

Agilent won a 2023 Environment+Energy Leader Award for Bond Elut PFAS WAX SPE Cartridges that improve efficiency in testing for PFAS substances, the so-called ‘forever chemicals.’ Bond Elut PFAS WAX enables scientists to confidently isolate PFAS from drinking water, wastewater, soil, sludge, tissues, and food. “The presence of PFAS chemicals in our daily lives is a grave concern,” the judges wrote, “making any technology that aids in their removal from the environment truly lifesaving.”

Per- and Polyfluoroalkyl Substances (PFAS) Analysis For Environmental Samples

Agilent offers complete end-to-end workflows for extraction, quantification even at Ultra-trace levels, and reporting of PFAS in the environment. This includes a range of sample preparation products, HPLC columns, chemical standards, PFC-free sample containment and other HPLC supplies, Ultra-high performance liquid chromatography (UHPLC) coupled to triple quadrupole mass spectrometry, e-methods, as well as gas chromatography products for sampling and analyzing a challenging range of trace-level volatile and semivolatile vapors of PFAS in air.

Full Workflow for US EPA Method 1633 for Targeted PFAS Analysis

Agilent announced a highly-anticipated, complete workflow solution for targeted per- and polyfluoroalkyl substances (PFAS) analysis using the United States (US) Environmental Protection Agency (EPA) Method 1633 (3rd draft). EPA Draft Method 1633 currently analyzes 40 PFAS compounds in wastewater and soil and is a complex and labor-intensive method, relying on multiple sample preparation and analysis steps. Success in running the technique depends on careful sample handling and the appropriate sample preparation supplies and instrumentation.

Featured Training & Events

The PFAS Lab of the Future

This webinar looks at the future of a PFAS lab - optimized workflows, maximum efficiency, artificial intelligence, and increased throughput.

Analysis of PFAS: Strategies to optimize performance

This expert discussion forum addresses some of the key issues surrounding the targeted analysis of PFAS in environmental matrices.

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