CD11b
The antibody reacts specifically with a leucocyte surface receptor (CR3) for the C3bi complement fragment. CD11b is expressed by most granulocytes and monocytes as well as a subpopulation of 'null cell' peripheral lymphocytes containing most of the circulating natural killer cells. CD11b (Mac-1) is the specific α-chain in the CD11b/CD18 molecule, which is a member of the LFA-1 and ß2 integrin subfamilies.
Further information and references to relevant literature are available in the products Instructions For Use.