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Infectious Disease Research Designs
Agilent community designs offer NGS designs targeting many pathogens, including bacteria and viruses. The designs are for deep sequencing of pathogen genomes, and they enable target enrichment of pathogen sequences from human samples for infectious disease research.
These designs were developed by our customers with considerable expertise in pathogen studies and infectious disease research. They are now available to Agilent customers as catalog made-to-order products.
Agilent has not performed verification and validation on these panels.
These designs were developed by our customers with considerable expertise in pathogen studies and infectious disease research. They are now available to Agilent customers as catalog made-to-order products.
Agilent has not performed verification and validation on these panels.
For Research Use Only. Not for use in diagnostic procedures.
- Community Designs (NGS)
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Product Details
Features
- NGS designs targeting pathogens for infectious disease research
- Design content developed by field experts with extensive expertise in infectious disease research
- High-quality probe libraries produced using the Agilent oligonucleotide library synthesis process
Literature
- Application Notes
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Application Note - SureSelect Target Enrichment for Whole Genome Sequencing - 5994-0909EN
Modifications when using SureSelect protocols for targeted enrichment of viral and bacterial whole genomes
- Application Notes
- English
- 24 Jul 2019
- 655.36 KB
- Brochures
- Flyers
Featured References
- Publications
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- Williams, R.J.; Tuthill, H.; Roy, S.; Romero, E.Y.; Williams, C.A. Breuer, J.; Depledge, D. Utilization of Agilent SureSelect Target Enrichment for Whole Genome Sequencing of Viruses and Bacteria. Agilent Application Note. 2019, PN 5994-0909EN. Learn More
- Clark, S.A.; Doyle, R.; Lucidarme, J.; Borrow, R.; Breuer, Targeted DNA enrichment and whole genome sequencing of Neisseria meningitidis directly from clinical specimens. Int. J. Med. Microbiol. 2018, 308: 256-262. Learn More
- Houldcroft, C.J.; Roy, S.; Morfopoulou, S.; Margetts, B.K.; Delpedge, D.P.; Cudini, J.; Shah, D.; Brown, J.R.; Romero, E.Y. Williams, R.; Cluotman-green, E.; Ro, K.; Standing, J.F.; Hartley, J.C. Breuer, J. Use of whole-genome sequencing of adenovirus in immunocompromised pediatric patients to identify nosocomial transmission and mixed-genotype infection. J. Infect. Dis. 2018, 218:1261-1271. Learn More
- Brown, J.; Roy, S.; Ruis, C.; Romero, E.; Shahb D.; Williams, R.; Breuera, J. Norovirus Whole-Genome Sequencing by SureSelect Target Enrichment: a Robust and Sensitive Method. J. Clin. Microbiol. 2016, 54:2530-2537. Learn More
- Lassalle, F.; Depledge, D.P.; Reeves, M.B.; Brown, A.C.; Christiansen M.T.; Tutill, H.J.; Williams, R.J.; Einer-Jensen, K.; Holdstock, J.; Atkinson, C.5.; Brown; J.R.; van Loenen, F.B.; Clark, D.A.; Griffiths P.D.; Verjans, G.M.; Schutten, M.; Milne, R.S.B.; Balloux, F.; Breuer, J. Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes. Virus Evol. 2106, 2(1): vew017. doi: 10.1093/ve/vew017. eCollection 2016 Jan. Learn More
- Thomson, E.; Ip, C.L.; Badhan, A.; Christiansen, M.T.; Adamson, W.; Ansari, M.A.; Bibby, D.; Breuer, J.; Brown, A.; Bowden, R.; Bryant, J.; Bonsall, D.; Da Silva Filipe, A.; Hinds, C.; Hudson, E.; Klenerman, P.; Lythgow, K.; Mbisa, J.L.; McLauchlan, J.; Myers, R.; Piazza, P.; Roy, S.; Trebes, A.; Sreenu, V.B.; Witteveldt, J.; STOP-HCV Consortium; Barnes, E.; Simmonds, P. Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes. J. Clin. Microbiol. 2016, 54: 24790-2484. Learn More
- Brown, A.C.; Bryant, J.M.; Einer-Jensen, K.; Holdstock, J.; Houniet, D.T.; Chan, J.Z., Depledge, D.P.; Nikolayevskyy, V.; Broda, A.; Stone, M.J.; Christiansen, M.T.; Williams, R.; McAndrew, M.B.; Tutill, H.; Brown J.; Melzer, M.; Rosmarin, C.; McHugh, T.D.; Shorten, R.J.; Drobniewski, F.; Speight, G.; Breuer, J. Rapid Whole-Genome Sequencing of Mycobacterium tuberculosis Isolates Directly from Clinical Samples. J. Clin. Microbiol. 2015, 53(7):2230-7. Learn More
- Christiansen, M.T.; Brown, A.C.; Kundu, S.; Tutill, H.J.; Williams, R.; Brown, J.R.; Holdstock, J.; Holland, M.J.; Stevenson, S.; Dave, J.; Tong, C.Y.; Einer-Jensen, K.; Depledge, D.P.; Breuer, J. Whole-genome enrichment and sequencing of Chlamydia trachomatis directly from clinical Samples. BMC Infect Dis. 2014, 14:591. Learn More
- Depledge, D.P.; Palser, A.L.; Watson, S.J.; Lai, A.I.; Gray, E.R.; Grant, P.; Kanda, R.K.; Leproust, E.; Kellam, P.; Breuer, J. Specific capture and whole-genome sequencing of viruses from clinical samples. PLos One. 2012, 7 (1) doi:10.1371/annotation/3f1444bc-ab9d-4112-958a-2e068792f26f. Learn More
Customer Testimonials
Judith Breuer
Co-director, Division of Infection and Immunity, University College London
SureSelect target enrichment enables highly efficient whole pathogen genome sequencing without the need for prior culture or PCR. The robust and consistent performance of SureSelect is why we’ve been depending on it for over 10 years.
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