Bio-Inert Analytical-Scale LC Purification System
1260 Infinity III Bio-Inert Analytical-Scale LC Purification System
This bio analytical preparative HPLC system comes with metal-free components in the sample flow path. The absence of iron and steel in solvent delivery lines ensure the integrity of your biomolecules, minimize unwanted surface interactions, and increase column lifetime.
The power range of this bio-inert HPLC purification system expands from low pressure, for traditional biopurification columns, up to high pressure, for sub-2-micron analytical biocolumns. The 1260 Infinity III Bio-Inert Fraction Collector offers a cooling module to prevent degradation of thermally labile biomolecules. Buffer Advisor software facilitates faster pH scouting and easy buffer/solvent preparation for ion-exchange chromatography (IEX).
- Preparative HPLC Systems
Product Details
- The metal-free sample flow path at 600 bar offers reliable analysis of biological samples and means that none of your precious sample will touch the metal surfaces, minimizing unwanted surface interactions while increasing column lifetime.
- Inert flow cells for UV and fluorescence detection as well as inert solvent and column selection valves for multimethod/multi-attribute analysis, offering instrument variety for highest adaptability.
- High salt tolerance (2 M) and wide pH range (1 to 13, short term 14) with active seal wash and quaternary solvent blending, offering increased flexibility.
- The 1260 Infinity III Bio-Inert Multisampler is designed for low carryover using a multiwash capability, reducing carryover to less than 9 ppm.
- Novel bio-inert capillary and connection design as well as InfinityLab Quick Connect and Quick Turn column fittings, offering ease of use.
- Faster pH scouting and easy buffer/solvent preparation for ion exchange chromatography (IEX) with Buffer Advisor software, simplifying bioanalysis workflows and reducing buffer preparation time.
- The AdvanceBio column portfolio is suitable for size-exclusion chromatography (SEC), IEX, reversed-phase LC, and peptide mapping, optimizing flexibility.
- Collection of up to 4 x 96 fractions in microtiter plates, or up to 216 fractions in glass tubes—with four different outer diameters available, increasing flexibility.
- Integrated and automated fraction delay sensor technology, increasing purity and recovery of collected fractions.
- Upgradable fraction capacity based on your demand, improving lab efficiency through orthogonal analytical information that is only available from isolated compounds.
- Mobile Phase Delivery
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1260 Infinity III Bio-Inert Pump
Quaternary solvent delivery for biological and extreme pH applications up to 600 bar.
- Sample Introduction
- Column Handling
- Detection
- Fraction Collection
- Recommended Accessories
- Application Software
- Key Literature
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Principles and Practical Aspects of Preparative Liquid Chromatography
This primer gives a comprehensive introduction to the basic principles of preparative liquid chromatography.
- Primers
- English
- 14 Oct 2019
- 4.58 MB
Purify Your Samples with Maximum Flexibility
Agilent InfinityLab LC Purification Solutions offer high-performance instrumentation, columns, software, and services for analytical- to preparative-scale workflows.
- Brochures
- English
- 08 Oct 2021
- 1.95 MB
Purify Your Way
Agilent Load & Lock Columns are ideal for routine purification of large quantities of material. Download brochure to learn more.
- Brochures
- English
- 03 Jan 2022
- 2.68 MB
- Brochures
- Selection Guides
- White Papers
- FAQs
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Which Preparative HPLC system fits your workflow?
HPLC, UHPLC, and LC/MSD Purification systems are available for various workflows, ensuring the highest purity and recovery. Read the guide
Infinity III LC Series: Your FAQs, answered
Find answers to FAQs about InfinityLab Assist, InfinityLab Level Sensing, and InfinityLab Sample ID Reader.
HPLC Fundamentals and FAQs
Learn HPLC and UHPLC basics and principles, including frequently asked questions, to help you be confident in your HPLC results. Read HPLC fundamentals now.
- Quick Reference Guides
- Site Preparation Checklists
- Supplemental Information
- User Manuals
Agilent InfinityLab HPLC Advisor
This one comprehensive app provides tools and information for your daily HPLC workflow.
HPLC Application Finder
Search for Preparative HPLC and LC Purification Application Notes and Technical Overviews
Essential Supplies for HPLC Purification Systems
Discover the supplies you need to achieve peak performance with your InfinityLab Preparative HPLC system.
HPLC/UHPLC Upgrades
Discover how you can enhance your lab efficiency and upgrade your existing HPLC/UHPLC systems and components.
Videos
Agilent introduces the Infinity III LC Series, transforming HPLC technology
Agilent Technologies launched the Infinity III LC Series, including the 1290 Infinity III LC, 1260 Infinity III Prime LC, and 1260 Infinity III LC systems. The systems feature InfinityLab Assist Technology for automation of daily HPLC tasks, system troubleshooting, and diagnostics. The new systems are designed to improve lab efficiency and reduce errors, promoting sustainability with My Green Lab’s ACT Ecolabel 2.0.
- 21 Oct 2024
Agilent Wins Two Scientists’ Choice Awards for Best New Analytical Product of 2024 and Excellence in Analytical Science Communication
Agilent Technologies Inc. received two prestigious Scientists’ Choice Awards: 2024 Webinar of the Year for “HPLC Made for Tomorrow: Introducing the new Agilent Infinity III LC Series” and Best New Analytical Product of 2024 for the Agilent 7010D Triple Quadrupole GC/MS System. These awards, voted on by the global scientific community, recognize Agilent's leadership in innovative technologies and impactful scientific education.
- 03 Jun 2025