Solvent Additives

Solvent additives like formic acid and ammonium formate are essential in HPLC and LC/MS methods to improve peak shape, separation, and ionization efficiency. These volatile additives control pH, reduce ion suppression, and enhance detection sensitivity in positive or negative ion modes.

Commonly used in pharmaceutical, environmental, and food testing, LC and LC/MS solvent additives optimize LC/MS performance while maintaining compatibility with mass spectrometry detection.