6230B Time of Flight (TOF) LC/MS
MS/MS applications are also supported by using fragments formed in the desolvation region of the TOF system ion source. All Ions MS/MS software then allows highly confident target compound identification by matching fragmentation patterns with an Agilent MS/MS library. Other advanced and intuitive software tools like one-click SWARM autotune and Walkup software allow anyone to routinely achieve reliable results.
- Time of Flight LC/MS
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Product Details
- Reduce false-positives with better than 1 ppm mass accuracy
- Ensure excellent data quality even for fast UHPLC peaks in high-throughput workflows with data acquisition rates up to 44 spectra/second
- Identify compounds based on accurate mass, isotopic abundance, and chemical composition using Find by Formula in MassHunter software
- Analyze monoclonal antibodies (mAb) with high mass accuracy and resolving power for glycoforms and truncation
- Characterize large biologic compounds with a broad mass range of up to 20,000 m/z
- Separate target compounds from interferences with high-resolution data
- Find impurities at extremely low concentrations, using Agilent Jet Stream technology with low picogram on-column sensitivity
- Identify trace-level target compounds in the presence of more abundant matrix compounds with up to five orders of in-spectrum dynamic range
- Reduce administrative tasks and risks while eliminating the need for LC/MS expertise with intuitive MassHunter Walkup software
- Perform untargeted screening with optional fragmentation data using in-source induced dissociation
- Go beyond UHPLC separation with support for capillary electrophoresis, SFC, 2D-LC, and even GC-APCI chromatographic interfaces
- Key Literature
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Analysis of Monoclonal Antibodies
Using Multiple Heart-cutting Hydrophobic Interaction/Reversed Phase 2D-LC/MS
- Application Notes
- English
- 03 Feb 2016
- 778.87 KB
Metabolomics Batch Data Analysis Workflow to Characterize Differential Metabolites in Bacteria
"This discovery metabolomics application uses Q-TOF LC/MS to identify and understand the biological and biochemical nature of bacterium.
- Application Notes
- English
- 28 Apr 2015
- 3.21 MB
Rapid and Accurate Forensics Analysis using High Resolution “All Ions MS/MS”
This application note describes the use of a new technique, “All Ions MS/MS”, to rapidly screen and identify drugs of forensic toxicological interest.
- Application Notes
- English
- 01 Mar 2018
- 2.11 MB
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Agilent Chromatography and Mass Spec Educational Webinar Series
Join Agilent Application Specialists as they present application-specific webinars to help you achieve the best results from your chromatography and mass spec experiments.
Peptide Mapping Using LC/MS
A step-by-step workflow review of peptide mapping using LC/MS
Emerging Omics Webinar Series
This ongoing webinar series will cover topics of interest to researchers using genomics, transcriptomics, proteomics, and metabolomics.
We hope you enjoyed ASMS 2022!
If you missed us in Minneapolis, you can still access our exciting mass spectrometry news online.
- 18 May 2022
Agilent Announces New Oligonucleotide Analysis Software for Biopharma Research
Agilent MassHunter BioConfirm 12.0 software introduces enhancements to existing capabilities for protein analysis and adds support for ligonucleotide analysis. The addition of oligonucleotide support significantly extends the capabilities of MassHunter BioConfirm, adding critical functionality for assessing oligonucleotide purity and sequence confirmation – important analytical steps in the use of oligonucleotides for biotherapeutics and vaccine research and development.
- 05 Jun 2022