Reacts with renal cell carcinoma marker (gp200), a surface membrane glycoprotein. The antigen is expressed on the brush border of proximal renal tubules and on the luminal surface of Bowman's capsule, as well as in parathyroid parenchymal cells and colloid of thyroid follicles. The antibody is a useful aid for classification of primary and metastatic renal cell carcinomas.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Formalin
HIER
Clone
SPM314
Code Number
M3632
Immunogen
Microsomal fraction of human renal cortical tissue homogenate.
Isotype
IgG2b, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as cell culture supernatant (containing fetal bovine serum) dialyzed against 0.02 mol/L PBS, pH 6.2, and containing 0.015 mol/L sodium azide.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
In Western blotting of Caki-1 cell lysate, the antibody labels a band of approximately 200 kDa corresponding to the expected molecular weight of renal cell carcinoma marker (8). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.