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Prostate-Specific Membrane Antigen (Autostainer Link 48)

Prostatic intraepithelial neoplasia (PIN)

Prostate-Specific Membrane Antigen (Autostainer Link 48)

Clone 3E6

Prostate-specific membrane antigen (PSMA) is expressed in normal and malignant prostatic epithelium and in a subset of non-prostatic tissues. In prostate cancer, PSMA expression has been shown to correlate with disease progression, with highest levels expressed in hormone-refractory and metastatic disease. The cellular localization of PSMA is cytoplasmic and/or membranous.

This antibody labels PSMA-expressing cells in normal and neoplastic tissues and is a useful aid for classification of prostate adenocarcinomas.

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