Progesterone receptor (PR) is a steroid hormone receptor that plays an important role in breast cancer. The absence of PR and estrogen receptor (ER) predicts early recurrence and poor survival of breast cancer patients. The antibody to PR is useful for measuring the relative level of expression of progesterone receptor in breast cancer tissue. This antibody is indicated for assessment of progestrerone receptor status in breast cancer.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Formalin
HIER
Clone
PgR 636
Code Number
M3569
Immunogen
Formalin-fixed recombinant full-length A-form of human progesterone receptor (1). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as tissue culture supernatant in 0.05 mol/L Tris-HCl, pH 7.2 and 0.015 mol/L sodium azide. This product contains stabilizing protein.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
Anti-PR, PgR 636 has been demonstrated to react with the PR-A and PR-B forms by Western blot of whole cell extracts and reacts with both free and hormone-bound PR (1). The epitope has been mapped to the amino terminal domain shared by PR-A and PR-B. See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.