Progesterone receptor (PR) is a steroid hormone receptor that plays an important role in breast cancer. The absence of PR and estrogen receptor (ER) predicts early recurrence and poor survival of breast cancer patients. The antibody to PR is useful for measuring the relative level of expression of progesterone receptor in breast cancer tissue. This antibody is indicated for assessment of progestrerone receptor status in breast cancer.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
PgR 636
Code Number
IR068
Immunogen
Formalin-fixed recombinant full-length A-form of human progesterone receptor (1). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN3.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
Anti-PR, PgR 636 has been demonstrated to react with the PR-A and PR-B forms by Western blot of whole cell extracts and reacts with both free and hormone-bound PR (1). The epitope has been mapped to the amino terminal domain shared by PR-A and PR-B. See p