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Octamer-Binding Transcription Factor 3/4 (Autostainer Link 48)

Embryonal carcinoma

Octamer-Binding Transcription Factor 3/4 (Autostainer Link 48)

Clone N1NK

Octamer-binding transcription factor 3/4 (OCT3/4) is expressed in early embryonic cells and germ cells and is central to the gene regulatory network responsible for self-renewal, pluripotency, and lineage commitment in embryonic stem cells and induced pluripotent stem cells (1).
Antibodies to OCT3/4 may be a useful aid for classification of specific subtypes of germ cell tumors including seminoma, embryonal carcinoma and intratubular germ cell neoplasia of unclassified type (IGCNU) (2, 3).

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