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MyoD1 (Concentrate)

MyoD1 (Concentrate)

Clone 5.8A

The MyoD1 protein is a 45 kDa nuclear phosphoprotein which induces myogenesis through transcriptional activation of muscle-specific genes. Nuclear expression of MyoD1 is restricted to skeletal muscle tissue and has been demonstrated to be a sensitive marker of myogenic differentiation. The antibody strongly labels the nuclei of myoblasts in developing skeletal muscle tissue, whereas the majority of adult skeletal muscle is negative. Results aid in the classification of rhabdomyosarcomas of various histological subtypes.

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