Colorectal carcinoma

MutS Protein Homolog 6 (Dako Omnis)

Clone EP49

Mismatch repair gene hMSH6 is a ubiquitous gene encoding the mismatch repair protein (MMR) known as MutS Protein Homolog 6 (MSH6). MSH6 is utilized by normal proliferating cells to repair point mutations that may occur during DNA replication. Antibodies to MSH6 are a useful aid for classification of colorectal cancer.

Monoclonal Rabbit Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.

Specifications


Application	Formalin HIER
Clone	EP49
Code Number	GA086
Form/Configuration	Ready-to-Use, FLEX
Immunogen	Synthetic peptide corresponding to residues at the N-terminus in human MSH6 protein.
Isotype	Rabbit Ig
Reagent Provided	Ready-to-use monoclonal rabbit antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide. Clone: EP49. Isotype: Rabbit IgG.
Solutions	Dako Omnis
Species	Rabbit Anti-Human
Specificity	In Western blotting of human Colo-205 cell lysate, the antibody labels a major band at 153 kDa corresponding to the expected molecular weight of MSH6.

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MutS Protein Homolog 6 (Dako Omnis)

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