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MutL Protein Homolog 1 (Autostainer Link 48)

Clone ES05

Mismatch repair gene hMLH1 is a ubiquitous gene encoding the mismatch repair protein (MMR) known as MutL protein homolog 1 (MLH1). MLH1 is utilized by normal proliferating cells to repair point mutations that may occur during DNA replication. Antibodies to MLH1 are a useful aid for classification of colorectal cancer.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	ES05
Code Number	IR079
Immunogen	Recombinant protein corresponding to a 210 amino acid portion of the human MLH1 molecule.
Isotype	IgG1
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form as cell culture supernatant (containing fetal bovine serum) dialyzed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 0.015 mol/L NaN₃.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	In Western blotting of human Caco-2 cell lysate, the antibody labels a major band at 88 kDa corresponding to the expected molecular weight of MLH1 (14). See package insert for reference(s).

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MutL Protein Homolog 1 (Autostainer Link 48)

Product Details

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