MUM1 Protein (Dako Omnis)
Labels MUM1 protein in a subset of light zone germinal centre (GC) B cells (probably centrocytes and their progeny), plasma cells and activated T cells. Antibodies to MUM1 protein are a useful aid for classification of a wide spectrum of hematolymphoid neoplasms derived from these cells. Of non-hematolymphoid neoplasms only a proportion of melanomas are labeled (1, 2). Antibodies to MUM1 protein are a useful aid for subclassification of B-cell lymphomas (1-3).
- Monoclonal Mouse Anti-Human
No data to display
This product is not available for purchase by the general public.
Product Details
Features
- Optimized staining performance of both high and low-expression structures
- Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
- Crisp and clear staining with no background
- Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
- The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application |
|
Clone |
|
Code Number |
|
Immunogen |
|
Isotype |
|
Reagent Provided |
|
Solutions |
|
Species |
|
Specificity |
|
Literature
- Catalogs
-
Atlas of Controls
The Atlas of Controls illustrates the staining performance of each antibody in the FLEX Ready-to-Use system.
- Catalogs
- English
- 26 Mar 2024
- 37.78 MB
- Technical Overviews
Support
- Instructions for Use
-
Featured References
- Product Description References
-
1. Falini B, Fizzotti M, Pucciarini A, Bigerna B, Marafioti T, Gambacorta M, et al. A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood 2000,95,2084-92.
2. Natkunam Y, Warnke RA, Montgomery K, Falini B, van de Rijn M. Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol 2001,14:686-94.
3. Gaidano G, Carbone A. MUM1: a step toward the understanding of lymphoma histogenesis. Leukemia 2000,14:563-6.
Promotions