The antigen recognized by this antibody is present in normal human hepatocytes and is conserved in a majority of hepatocellular carcinomas (1). The antibody is a useful aid for classification of hepatocellular carcinomas. The antibody does not label other tumors, except for some rare tumors of gastrointestinal origin.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Frozen
Formalin
HIER
Clone
OCH1E5
Code Number
M7158
Immunogen
Formalin-fixed, failed human allograft liver that was mechanically disrupted (2). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN3.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
The antibody labels an antigen that seems to be localized to the mitochondrial fraction of liver homogenates (2). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.
1. Minervini MI, Demetris AJ, Lee RG, Carr BI, Madariaga J, Nalesnik MA. Utilization of hepatocyte-specific antibody in the immunocytochemical evaluation of liver tumors. Mod Pathol 1997,10:686-92.