H. pylori (formerly called Campylobacter pylori) is a spiral-shaped microaerophilic, Gram-negative rod with unipolar sheated flagella. It inhabits the mucus lining of the gastric epithelium. H. pylori is one of the most common pathogenic infections, which leads to serious gastroduodenal diseases in a subset of individuals. There is evidence supporting an association between H. pylori and chronic atrophic gastritis as well as gastric cancer. This antibody is useful for the identification of infections with H. pylori in gastritis and gastric cancer.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application
Formalin
HIER
Clone
Polyclonal
Code Number
GA523
Immunogen
The antigen for immunization was prepared from heat-treated cells of the H. pylori strain, CH-20426 (1, 2). See package insert for reference(s).
Reagent Provided
Ready-to-use polyclonal rabbit antibody provided in liquid form in a buffer containing stabilizing protein and 0.1 mol/L NaCl, 0.015 mol/L NaN3.
Solutions
Dako Omnis
Species
Rabbit Anti-
Specificity
The antibody labels heat-stable, somatic antigens of the whole H. pylori organism. Traces of contaminating antibodies have been removed by solid-phase absorption with human plasma proteins. In crossed immunoeletrophoresis, using 12.5 µL concentrated antibody per cm2 gel area against 2 µL of human plasma no precipitate appears. Staining: Coomassie Brilliant Blue.