H. pylori (formerly called Campylobacter pylori) is a spiral-shaped microaerophilic, Gram-negative rod with unipolar sheated flagella. It inhabits the mucus lining of the gastric epithelium. H. pylori is one of the most common pathogenic infections, which leads to serious gastroduodenal diseases in a subset of individuals. There is evidence supporting an association between H. pylori and chronic atrophic gastritis as well as gastric cancer. This antibody is useful for the identification of infections with H. pylori in gastritis and gastric cancer.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years’ experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Formalin
Enzyme/HIER
Clone
Polyclonal
Code Number
B0471
Immunogen
The antigen for immunization was prepared from heat-treated cells of the H. pylori strain, CH-20426 (1, 2). See package insert for reference(s).
Reagent Provided
Purified immunoglobulin fraction of rabbit antiserum provided in liquid form in 0.1 mol/L NaCl, 15 mmol/L NaN3.
Solutions
Concentrate
Species
Rabbit Anti-
Specificity
The antibody labels heat-stable antigens of the H. pylori organism. Traces of contaminating antibodies have been removed by solid-phase absorption with human plasma proteins. In crossed immunoelectrophoresis, using 12.5 µL antibody per cm 2 gel area against 2 µL of human plasma no precipitate appears. Staining: Coomassie Brilliant Blue.
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.
