Gross cystic disease fluid protein-15 (GCDFP-15) is a 15 kDa monomeric secretory glycoprotein encoded by the prolactin-inducible protein (PIP) gene. GCDFP-15 is a marker of apocrine differentiation, and is expressed in breast cystic fluid as well as in apocrine, lacrimal, ceruminous, Moll's and eccrine glands. Antibodies to GCDFP-15 are a useful aid for classification of breast carcinoma and metastatic tumors of breast origin.
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Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Formalin
HIER
Clone
23A3
Code Number
M3638
Immunogen
Recombinant protein corresponding to the excreted domain of the gross cystic disease fluid protein (15 kDa) molecule.
Isotype
IgG2a, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as cell culture supernatant in 0.05 mol/L Tris-HCl, pH 7.2, and 0.015 mol/L sodium azide.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
In Western blotting of human MDA-MB-361 cell lysate, the antibody labels a 15 kDa band corresponding to the expected molecular weight of GCDFP-15 (13). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.