E-Cadherin (Dako Omnis)

Clone NCH-38

E (epithelial)-cadherin is a 120 kDa transmembrane cell adhesion molecule. It has a significant function in intercellular adhesion of epithelial cells, the establishment of epithelial polarization, glandular differentiation and stratification. Down-regulation of E-cadherin expression has been observed in a number of carcinomas and is usually associated with advanced stage and progression. The antibody is a useful aid for classification of ductal breast carcinomas.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.

Specifications


Application	Formalin HIER
Clone	NCH-38
Code Number	GA059
Immunogen	E-cadherin (uvomorulin) recombinant protein (4). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN₃.
Solutions	Dako Omnis
Species	Mouse Anti-Human
Specificity	Anti-E-cadherin, NCH-38 recognizes the 120 kDa mature form and 82 kDa fragment of E-cadherin in Western blots of A431 cells lysates (4). See package insert for reference(s).

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E-Cadherin (Dako Omnis)

Product Details

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