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E-Cadherin (Autostainer Link 48)

Liver

E-Cadherin (Autostainer Link 48)

Clone NCH-38

E (epithelial)-cadherin is a 120 kDa transmembrane cell adhesion molecule. It has a significant function in intercellular adhesion of epithelial cells, the establishment of epithelial polarization, glandular differentiation and stratification. Down-regulation of E-cadherin expression has been observed in a number of carcinomas and is usually associated with advanced stage and progression. The antibody is a useful aid for classification of ductal breast carcinomas.

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