Uterine leiomyoma

Desmin (Autostainer Link 48)

Clone D33

Labels smooth and striated muscle cells. The antibody works on paraffin-embedded material without pretreament with proteolytic enzymes. Anti-Desmin, clone D33, is a useful aid for classification of tumors of uncertain origin.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	D33
Code Number	IR606
Immunogen	Desmin purified from human muscle.
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	In Western blotting of cytoskeletal preparations of MCF-7 cells, SCC-4 cells RT-112 cells, skin epidermis, primary culture of renal carcinoma cells, leiomyoma, fetal heart, and crude extract from human white matter of brain, the antibody labels only a ~53 kDa band in the leiomyoma and fetal heart preparations, proving the reactivity with desmin, and demonstrating the absence of reactivity with other types of intermediate filaments tested (7). See package insert for reference(s).

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