Labels smooth and striated muscle cells. The antibody works on paraffin-embedded material without pretreament with proteolytic enzymes. Anti-Desmin, clone D33, is a useful aid for classification of tumors of uncertain origin.
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Desmin purified from human muscle.
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Autostainer Link 48
In Western blotting of cytoskeletal preparations of MCF-7 cells, SCC-4 cells RT-112 cells, skin epidermis, primary culture of renal carcinoma cells, leiomyoma, fetal heart, and crude extract from human white matter of brain, the antibody labels only a ~53 kDa band in the leiomyoma and fetal heart preparations, proving the reactivity with desmin, and demonstrating the absence of reactivity with other types of intermediate filaments tested (7). See package insert for reference(s).
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