Reacts with the 68 kDa, 58 kDa, 56.5 kDa and 50 kDa proteins corresponding to cytokeratins 1, 5, 10 and 14. The antibody labels squamous, ductal and complex epithelia. Results aid in the classification of prostatic adenocarcinoma and in the classification of neoplastic tissue as carcinoma of epithelial origin.
Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application
Formalin
HIER
Clone
34βE12
Immunogen
Solubilized immunogen keratin extracted from human stratum corneum (1). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN3.
Solutions
Dako Omnis
Species
Mouse Anti-Human
Specificity
Anti-Cytokeratin, High Molecular Weight (Anti-CK HMW), 34βE12 has been shown to react with the 66, 57, 51 and 49 kDa proteins in Western blotting corresponding to cytokeratins 1, 5, 10 and 14 of the Moll catalog (1, 2, 4). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.
