Reacts with the 54 kDa protein corresponding to cytokeratin 7. The antibody labels several types of normal and neoplastic epithelia, including many ductal and glandular epithelia. The antibody is a useful aid for classification of adenocarcinomas of the lung, breast and endometrium, thyroid gland and ovary, as well as chromophobe renal cell carcinomas. Results may also aid in the classification of prostate carcinomas where CK7 is rarely expressed.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Frozen
Formalin
Enzyme/HIER
Clone
OV-TL 12/30
Code Number
M7018
Immunogen
OTN 11, ovarian carcinoma cell line (1, 8). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN3.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
In one- and two-dimensional SDS-PAGE and immunoblotting of Triton X-100-extracted cytoskeleton preparations of several cell cultures and tissues, the antibody labeled a 54 kDa band corresponding to cytokeratin 7 (1). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.