Reacts strongly with cytokeratins 5 and 6 and weakly with cytokeratin 4. The antibody does not cross-react with cytokeratins 1, 7, 8, 10, 13, 14, 18 and 19. It labels mesothelioma, and epithelial basal cells in prostate and tonsil. No reactivity with other mesodermally derived tissues, such as muscle and connective tissues, has been observed. The antibody is a useful aid for classification of epithelioid mesotheliomas.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application
Formalin
HIER
Clone
D5/16 B4
Code Number
GA780
Immunogen
Isolated cytokeratin 5.
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Dako Omnis
Species
Mouse Anti-Human
Specificity
In Western blotting of cytoskeletal preparations of epidermis and non-keratinizing epithelium, the antibody labels cytokeratin 5. It also labels cytokeratin 6 and weakly labels cytokeratin 4. No cross-reaction with cytokeratins 1, 7, 8, 10, 13/14, 18 and 19 has been found.