Renal clear cell carcinoma

Cytokeratin 18 (Dako Omnis)

Clone DC 10

Reacts with the 45 kDa protein corresponding to cytokeratin 18. The antibody labels a large number of simple epithelia, including many ductal and glandular epithelia. The antibody is a useful aid for classification of tumors of epithelial origin. In vascular tumors, the antibody may be a useful aid in the classification of epithelioid hemangioendotheliomas.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.

Specifications


Application	Formalin HIER
Clone	DC 10
Code Number	GA618
Immunogen	PCM 42, human breast carcinoma cell line (7). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Dako Omnis
Species	Mouse Anti-Human
Specificity	In Western blotting of cytokeratin preparations from BT 20 cells, the antibody labels a single band of 45 kDa corresponding to CK18 (7). In immunocytochemistry on human cultured cell lines, the antibody labels tumor cells of epithelial origin, whereas normal fibroblasts and tumor cells of non-epithelial origin such as glioma, melanoma and osteosarcoma, are not labeled (7). See package insert for reference(s).

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Featured References

Product Description References: 1. Lauerova L, Kovarik J, Bartek J, Rejthar A, Vojtesek B. Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule. Hybridoma 1988,7:495-504.

Cytokeratin 18 (Dako Omnis)

Product Details

Atlas of Controls

View supported Instructions For Use documents

1. Lauerova L, Kovarik J, Bartek J, Rejthar A, Vojtesek B. Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule. Hybridoma 1988,7:495-504.

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