CD8 is a 68 kDa transmembrane glycoprotein expressed as a heterodimer by a majority of thymocytes, and by class I major histocompatibility complex restricted, mature, suppressor/cytotoxic T cells. The antibody is a useful aid for classification of cytotoxic/suppressor T-cell lymphomas.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years experience ensuring quality and innovation in antibodies and reagents
Specifications
Application
Frozen
Formalin
HIER
Clone
C8/144B
Code Number
M7103
Immunogen
Synthetic peptide corresponding to the 13 C-terminal amino acids of cytoplasmic domain of human CD8α coupled to thyroglobulin (1). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN3.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
SDS-PAGE analysis of immunoprecipitates formed between lysates of 125I-labeled human T lymphoblasts and the antibody shows reaction primarily with a 32 kDa polypeptide corresponding to CD8α (1). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.