Spleen

CD8 (Autostainer Link 48)

Clone C8/144B

CD8 is a 68 kDa transmembrane glycoprotein expressed as a heterodimer by a majority of thymocytes, and by class I major histocompatibility complex restricted, mature, suppressor/cytotoxic T cells. The antibody is a useful aid for classification of cytotoxic/suppressor T-cell lymphomas.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	C8/144B
Code Number	IR623
Immunogen	Synthetic peptide corresponding to the 13 C-terminal amino acids of cytoplasmic domain of human CD8α coupled to thyroglobulin (1). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	SDS-PAGE analysis of immunoprecipitates formed between lysates of ¹²⁵I-labeled human T lymphoblasts and the antibody shows reaction primarily with a 32 kDa polypeptide corresponding to CD8α (1). See package insert for reference(s).

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