CD79α Antibody (Autostainer Link 48)

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	JCB117
Immunogen	Recombinant protein containing part of the extracellular portion of the human CD79α glycoprotein (1). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	Anti-Human CD79α, clone JCB117, was clustered as anti-CD79α at the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens (4). In Western blotting of Ramos B-cell lysate, the antibody labels a band corresponding to CD79α under reducing conditions, and a band corresponding to CD79αß under non-reducing conditions (1). SDS-PAGE analysis of immunoprecipitates formed between the antibody and ¹²⁵I-labeled, mildly denatured, and reduced lysate of Ramos B cells, shows weak reaction with a 43 kDa polypeptide corresponding to CD79α. See package insert for reference(s).

Literature

Catalogs

The Atlas of Controls illustrates the staining performance of each antibody in the FLEX Ready-to-Use system.

Technical Overviews

Support

Material Safety Data Sheets

Material Safety Data Sheet

Featured References

Product Description References: 1. Mason DY, Cordell JL, Brown MH, Borst J, Jones M, Pulford K, et al. CD79a: a novel marker for B-cell neoplasms in routinely processed tissue samples. Blood 1995,86:1453-9.
2. Pilozzi E, Pulford K, Jones M, Muller-Hermelink HK, Falini B, Ralfkiaer E, et al. Co-expression of CD79a (JCB117) and CD3 by lymphoblastic lymphoma. J Pathol 1998,186:140-3.
3. Chu PG, Arber DA. CD79: a review. Appl Immunohistochem Mol Morphol 2001,9:97-106

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CD79α (Autostainer Link 48)